Strategies to package recombinant Adeno-Associated Virus expressing the N-terminal gasdermin domain for tumor treatment
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DOI: 10.1038/s41467-021-27407-0
Abstract: Pyroptosis induced by the N-terminal gasdermin domain (GSDMNT) holds great potential for anti-tumor therapy. However, due to the extreme cytoxicity of GSDMNT, it is challenging to efficiently produce and deliver GSDMNT into tumor cells. Here,… read more here.
Keywords: tumor; strategies package; gasdermin domain; terminal gasdermin ... See more keywords