Therapeutic strategies for Parkinson’s disease: promising agents in early clinical development
Sign Up to like & getrecommendations! Published in 2020 at "Expert Opinion on Investigational Drugs"
DOI: 10.1080/13543784.2020.1814252
Abstract: ABSTRACT Introduction To date, no drug has demonstrated clinically indisputable neuroprotective efficacy in Parkinson’s disease (PD). We also have no effective symptomatic treatment for disabling symptoms such as balance problems, and dementia, and we need… read more here.
Keywords: therapeutic strategies; strategies parkinson; parkinson disease; promising agents ... See more keywords
Emerging Therapeutic Strategies for Parkinson’s Disease and Future Prospects: A 2021 Update
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DOI: 10.3390/biomedicines10020371
Abstract: Parkinson’s disease (PD) is a neurodegenerative disorder pathologically distinguished by degeneration of dopaminergic neurons in the substantia nigra pars compacta. Muscle rigidity, tremor, and bradykinesia are all clinical motor hallmarks of PD. Several pathways have… read more here.
Keywords: therapeutic strategies; strategies parkinson; emerging therapeutic; etiology ... See more keywords
Neuroprotective Surgical Strategies in Parkinson’s Disease: Role of Preclinical Data
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DOI: 10.3390/ijms18102190
Abstract: Although there have been many pharmacological agents considered to be neuroprotective therapy in Parkinson’s disease (PD) patients, neurosurgical approaches aimed to neuroprotect or restore the degenerative nigrostriatal system have rarely been the focus of in… read more here.
Keywords: neuroprotective surgical; disease role; clinical trials; strategies parkinson ... See more keywords