Advancing Strategies for Proteolysis-Targeting Chimera Design.
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DOI: 10.1021/acs.jmedchem.2c01555
Abstract: Proteolysis-targeting chimeras (PROTACs) have shown great therapeutic potential by degrading various disease-causing proteins, particularly those related to tumors. Therefore, the introduction of PROTACs has ushered in a new chapter of antitumor drug development, marked by… read more here.
Keywords: targeting chimera; design; strategies proteolysis; proteolysis ... See more keywords