CRISPR-based enrichment strategies for targeted sequencing.
Sign Up to like & getrecommendations! Published in 2020 at "Biotechnology advances"
DOI: 10.1016/j.biotechadv.2020.107672
Abstract: The ability to easily produce or procure sequencing data has expanded to be within the reach of most clinics and research laboratories, but the complexity of sequence analysis remains a hurdle for many scientists, and… read more here.
Keywords: strategies targeted; enrichment strategies; crispr based; based enrichment ... See more keywords
Recent progress in LyP-1-based strategies for targeted imaging and therapy
Sign Up to like & getrecommendations! Published in 2019 at "Drug Delivery"
DOI: 10.1080/10717544.2019.1587047
Abstract: Abstract The identification of markers expressed by pathological cells or their microenvironment would help to distinguish such cells from the normal tissues. The strategies derived from this theory can be a promising modality for imaging… read more here.
Keywords: lyp based; strategies targeted; progress lyp; based strategies ... See more keywords
Nano-enabled strategies for targeted immunotherapy in gastrointestinal cancers
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2025.1653829
Abstract: Gastrointestinal (GI) cancers remain a leading cause of global cancer morbidity and mortality, demanding novel therapeutic strategies that overcome existing limitations. Nanomedicine has recently emerged as a transformative approach, offering the potential to significantly enhance… read more here.
Keywords: enabled strategies; immunotherapy gastrointestinal; nano enabled; strategies targeted ... See more keywords
Strategies for Targeted Delivery of Exosomes to the Brain: Advantages and Challenges
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics14030672
Abstract: Delivering therapeutics to the central nervous system (CNS) is difficult because of the blood–brain barrier (BBB). Therapeutic delivery across the tight junctions of the BBB can be achieved through various endogenous transportation mechanisms. Receptor-mediated transcytosis… read more here.
Keywords: brain; strategies targeted; receptor; bbb crossing ... See more keywords
Innovative Strategies for the Targeted Degradation of Viral Proteins: Paving the Way for Next-Generation Therapeutics
Sign Up to like & getrecommendations! Published in 2025 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics17111420
Abstract: Background/Objectives: This review discusses the development and application of targeted protein degradation strategies, particularly focusing on the ubiquitin–proteasome pathway and PROteolysis-TArgeting Chimeras (PROTAC) technology, for antiviral therapies. Methods/Results: The synthesis of specific PROTACs exemplifies the… read more here.
Keywords: viral proteins; proteins paving; strategies targeted; innovative strategies ... See more keywords