Emerging Strategies for Therapeutic Antibody Discovery from Human B Cells.
Sign Up to like & getrecommendations! Published in 2020 at "Advances in experimental medicine and biology"
DOI: 10.1007/978-981-15-4494-1_18
Abstract: Monoclonal antibodies from human sources are being increasingly recognized as valuable options in many therapeutic areas. These antibodies can show exquisite specificity and high potency while maintaining a desirable safety profile, having been matured and… read more here.
Keywords: strategies therapeutic; emerging strategies; antibody; discovery human ... See more keywords
Extracellular vesicles: intelligent delivery strategies for therapeutic applications
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Controlled Release"
DOI: 10.1016/j.jconrel.2018.09.019
Abstract: &NA; Extracellular vesicles (EV), in particular exosomes, have been the object of intense research, due to their potential to mediate intercellular communication, modulating the phenotype of target cells. The natural properties and functions of EV… read more here.
Keywords: extracellular vesicles; strategies therapeutic; intelligent delivery; delivery ... See more keywords
Targeting the mitochondrial chaperone TRAP1: strategies and therapeutic perspectives.
Sign Up to like & getrecommendations! Published in 2021 at "Trends in pharmacological sciences"
DOI: 10.1016/j.tips.2021.04.003
Abstract: TRAP1, the mitochondrial isoform of heat shock protein (Hsp)90 chaperones, is a key regulator of metabolism and organelle homeostasis in diverse pathological states. While selective TRAP1 targeting is an attractive goal, classical active-site-directed strategies have… read more here.
Keywords: mitochondrial chaperone; strategies therapeutic; trap1 strategies; chaperone trap1 ... See more keywords