Stimuli-responsive size-changeable strategy for cancer theranostics
Sign Up to like & getrecommendations! Published in 2021 at "Nano Today"
DOI: 10.1016/j.nantod.2021.101208
Abstract: Abstract It is essential to overcome many biological barriers and deliver theranostic agents to tumor sites. As a basic property of nanoagents, particle size plays an important role in the whole delivery process. However, at… read more here.
Keywords: changeable strategy; size changeable; cancer theranostics; strategy cancer ... See more keywords
PROTACs: a novel strategy for cancer therapy.
Sign Up to like & getrecommendations! Published in 2020 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2020.02.006
Abstract: Chemotherapeutic strategy has been widely used for treating malignance by targeting irregular expressed or mutant proteins with small molecular inhibitors (SMIs) or monoclonal antibodies (mAbs). However, most intracellular proteins lack of active sites or antigens… read more here.
Keywords: strategy cancer; protacs; cancer; novel strategy ... See more keywords
Advances in mechanism and treatment strategy of cancer.
Sign Up to like & getrecommendations! Published in 2018 at "Cellular and molecular biology"
DOI: 10.14715/cmb/2018.64.6.1
Abstract: Cancer is one of the most serious diseases with high incidence and high mortality rate threaten human health and quality of life. The researches on mechanisms of cancer development and metastasis, and effective and reasonable… read more here.
Keywords: strategy cancer; treatment; advances mechanism; treatment strategy ... See more keywords
Nitroreductase-induced bioorthogonal ligation for prodrug activation: A traceless strategy for cancer-specific imaging and therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Bioorganic chemistry"
DOI: 10.2139/ssrn.4156111
Abstract: Prodrug development is of great interest in cancer therapy. From bio-friendly standpoints, traceless prodrug activation would be an ideal approach for cancer treatment owning to the avoidance of byproduct which might induce side effects in… read more here.
Keywords: traceless strategy; strategy cancer; prodrug activation; therapy ... See more keywords
Targeting Ferroptosis Pathways: A Novel Strategy for Cancer Therapy.
Sign Up to like & getrecommendations! Published in 2022 at "Current cancer drug targets"
DOI: 10.2174/1568009622666220211122745
Abstract: Ferroptosis is an iron-dependent nonapoptotic kind of regulated cell death resulting from the destruction of redox balance in the cytosol. Unlike apoptosis, ferroptosis is caused by an increase in intracellular iron and lipid peroxides that… read more here.
Keywords: strategy cancer; cancer therapy; ferroptosis; cancer ... See more keywords
Ferroptosis: A New Strategy for Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Oncology"
DOI: 10.3389/fonc.2022.830561
Abstract: Ferroptosis is a newly discovered form of iron-dependent cell death, which is different from other death forms. The main characteristics of ferroptosis are: (1) Amino acid metabolism. (2) Iron metabolism; (3) Lipid metabolism and Reactive… read more here.
Keywords: iron; ferroptosis; strategy cancer; ferroptosis new ... See more keywords
The Switch between Protective and Nonprotective Autophagy; Implications for Autophagy Inhibition as a Therapeutic Strategy in Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Biology"
DOI: 10.3390/biology9010012
Abstract: Autophagy, a process of cellular self-degradation and cell survival whereby the cell generates energy and metabolic intermediates under conditions of stress (i.e., nutrient deprivation), is also commonly induced in tumor cells in response to chemotherapy… read more here.
Keywords: autophagy inhibition; therapeutic strategy; inhibition therapeutic; strategy cancer ... See more keywords
Aurora Kinase B Inhibition: A Potential Therapeutic Strategy for Cancer
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26071981
Abstract: Aurora kinase B (AURKB) is a mitotic serine/threonine protein kinase that belongs to the aurora kinase family along with aurora kinase A (AURKA) and aurora kinase C (AURKC). AURKB is a member of the chromosomal… read more here.
Keywords: inhibition potential; therapeutic strategy; strategy cancer; inhibition ... See more keywords
Targeting Ferroptosis by Ubiquitin System Enzymes: A Potential Therapeutic Strategy in Cancer
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Biological Sciences"
DOI: 10.7150/ijbs.73790
Abstract: Ferroptosis is a novel type of regulated cell death driven by the excessive accumulation of iron-dependent lipid peroxidation. Therapy-resistant tumor cells, particularly those in the mesenchymal-like state and prone to metastasis, are highly susceptible to… read more here.
Keywords: strategy cancer; ubiquitin system; ferroptosis; system enzymes ... See more keywords