Novel strategy for the preparation of 3-perfluoroalkylated-2H-indazole derivatives
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DOI: 10.1016/j.tetlet.2018.03.051
Abstract: Abstract A simple and novel methodology for the synthesis of 3-perfluoroalkylated-2H-indazole derivatives has been elaborated. The perfluoroalkylation of readily available 2-nitrobenzaldimines bearing electron donating groups was performed using the Ruppert-Prakash reagent and its analogues to… read more here.
Keywords: methodology; preparation perfluoroalkylated; perfluoroalkylated indazole; indazole derivatives ... See more keywords
New strategy for the preparation of imidazole derivatives containing thiazole ring via ring opening/coupling/cyclization/decarboxylation cascade
Sign Up to like & getrecommendations! Published in 2019 at "Tetrahedron Letters"
DOI: 10.1016/j.tetlet.2019.151194
Abstract: Abstract The aim of this work is to investigate the three-component reaction of 6-aminopenicillinic acid, aldehydes and ammonium acetate. The work was used SiO2-H2SO4 as a catalyst to promote the reaction under solvent-free conditions. A… read more here.
Keywords: derivatives containing; imidazole derivatives; preparation imidazole; new strategy ... See more keywords
A General Strategy for the Preparation of Thalidomide-Conjugate Linkers
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DOI: 10.1055/s-0036-1588539
Abstract: The synthesis of small-molecule linkers for installation of thalidomide-based conjugates is described. Linker properties have been recognized as vital to conjugate success in drug discovery and delivery systems. These small-molecule tethers act as linkages between… read more here.
Keywords: thalidomide conjugate; conjugate; preparation thalidomide; general strategy ... See more keywords