A combined tissue‐engineered/in silico signature tool patient stratification in lung cancer
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12323
Abstract: Patient‐tailored therapy based on tumor drivers is promising for lung cancer treatment. For this, we combined in vitro tissue models with in silico analyses. Using individual cell lines with specific mutations, we demonstrate a generic… read more here.
Keywords: stratification; treatment; tissue; drug ... See more keywords
High‐throughput proteomic analysis of FFPE tissue samples facilitates tumor stratification
Sign Up to like & getrecommendations! Published in 2019 at "Molecular Oncology"
DOI: 10.1002/1878-0261.12570
Abstract: Formalin‐fixed, paraffin‐embedded (FFPE), biobanked tissue samples offer an invaluable resource for clinical and biomarker research. Here, we developed a pressure cycling technology (PCT)‐SWATH mass spectrometry workflow to analyze FFPE tissue proteomes and applied it to… read more here.
Keywords: stratification; ffpe samples; tissue samples; ffpe ... See more keywords
Conjugated-Polymer Blends for Organic Photovoltaics: Rational Control of Vertical Stratification for High Performance.
Sign Up to like & getrecommendations! Published in 2017 at "Advanced materials"
DOI: 10.1002/adma.201601674
Abstract: The photoactive layer of bulk-heterojunction organic solar cells, in a thickness range of tens to hundreds of nanometers, comprises phase-separated electron donors and acceptors after solution casting. The component distribution in the cross-section of these… read more here.
Keywords: stratification; blends organic; conjugated polymer; polymer blends ... See more keywords
Deep‐Learning‐Assisted Stratification of Amyloid Beta Mutants Using Drying Droplet Patterns
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202110404
Abstract: The development of simple and accurate methods to predict mutations in proteins remains an unsolved challenge in modern biochemistry. It is discovered that critical information about primary and secondary peptide structures can be inferred from… read more here.
Keywords: drying droplet; amyloid beta; deep learning; stratification ... See more keywords
Proteomic Identification of Small Extracellular Vesicle Proteins LAMB1 and Histone H4 for Prostate Cancer Diagnosis and Risk Stratification
Sign Up to like & getrecommendations! Published in 2024 at "Advanced Science"
DOI: 10.1002/advs.202402509
Abstract: Diagnosis and stratification of prostate cancer (PCa) patients using the prostate‐specific antigen (PSA) test is challenging. Extracellular vesicles (EVs), as a new star of liquid biopsy, has attracted interest to complement inaccurate PSA screening and… read more here.
Keywords: diagnosis; cancer; stratification; risk ... See more keywords
Artificial Intelligence‐Driven Proteomics Identifies Plasma Protein Signatures for Diagnosis and Stratification of Behçet's Disease
Sign Up to like & getrecommendations! Published in 2025 at "Advanced Science"
DOI: 10.1002/advs.202510061
Abstract: The diagnosis of Behçet’s disease (BD) predominantly relies on clinical symptoms, indicating an urgent for identifying potential biomarkers for early diagnosis and disease stratification. We employed an in‐depth proteomics platform based on data‐independent acquisition mass… read more here.
Keywords: diagnosis; diagnosis stratification; disease; stratification ... See more keywords
Integration of multiparameter flow cytometry score improves prognostic stratification provided by standard models in primary myelofibrosis
Sign Up to like & getrecommendations! Published in 2022 at "American Journal of Hematology"
DOI: 10.1002/ajh.26548
Abstract: Prognostic modeling in myelofibrosis (MF) has classically pursued the integration of informative clinical and hematological parameters to separate patients' categories with different outcomes. Modern stratification includes also genetic data from karyotype and mutations. However, some… read more here.
Keywords: prognostic stratification; flow cytometry; multiparameter flow; stratification ... See more keywords
A new cytokine‐based dynamic stratification during induction is highly predictive of survivals in acute myeloid leukemia
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Medicine"
DOI: 10.1002/cam4.3648
Abstract: The aim of this study was to assess the potential impact of the kinetics of serum levels of seven cytokines during induction in acute myeloid leukemia (AML) patients. Indeed, the role of cytokines, in the… read more here.
Keywords: stratification; risk; myeloid leukemia; acute myeloid ... See more keywords
Histomorphological stratification of blubber of three dolphin species from subtropical waters
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Morphology"
DOI: 10.1002/jmor.21511
Abstract: Blubber is a highly specialized and dynamic tissue unique to marine mammals and presents a reflection of the individuals' nutrition, environment, and life history traits. Few studies have investigated the histomorphology of cetacean blubber in… read more here.
Keywords: cell; blubber; subtropical waters; stratification ... See more keywords
Late Quaternary record of Indian summer monsoon‐induced stratification and productivity collapse in the Andaman Sea
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Quaternary Science"
DOI: 10.1002/jqs.3278
Abstract: During each summer monsoon, the northeastern Indian Ocean receives a huge amount of rain and river discharge, resulting in strong stratification and prevalence of oligotrophic conditions. These water column changes impact upper ocean productivity which… read more here.
Keywords: summer monsoon; stratification; stratification productivity; productivity ... See more keywords
Atmospheric stilling and warming air temperatures drive long‐term changes in lake stratification in a large oligotrophic lake
Sign Up to like & getrecommendations! Published in 2020 at "Limnology and Oceanography"
DOI: 10.1002/lno.11654
Abstract: Lake surface temperatures are warming in many regions and have the potential to alter seasonal thermal stratification. However, the effects of climate change on thermal stratification can be difficult to characterize because trends in thermal… read more here.
Keywords: long term; stratification; lake; air temperatures ... See more keywords