Stream-lined synthesis of 3-hydroxy-β-lactams: Norrish-Yang type II photocyclizations of β-ketoformamides
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DOI: 10.1016/j.tet.2018.04.040
Abstract: Abstract A photochemical approach to 3-phenyl-3-hydroxy-β-lactams (3-HβLs) is reported. Irradiation of aryl-β-ketoformamides with a UV light band centered at 300 nm provides the corresponding 3-aryl-3-HβLs with good conversion. The scope of the photocyclization is explored with… read more here.
Keywords: norrish yang; stream lined; yang type; hydroxy lactams ... See more keywords