Glycan‐metabolizing enzymes in microbe–host interactions: the Streptococcus pneumoniae paradigm
Sign Up to like & getrecommendations! Published in 2018 at "FEBS Letters"
DOI: 10.1002/1873-3468.13045
Abstract: Streptococcus pneumoniae is a frequent colonizer of the upper airways; however, it is also an accomplished pathogen capable of causing life‐threatening diseases. To colonize and cause invasive disease, this bacterium relies on a complex array… read more here.
Keywords: streptococcus pneumoniae; metabolizing enzymes; host; glycan metabolizing ... See more keywords
Triosephosphate isomerase of Streptococcus pneumoniae is released extracellularly by autolysis and binds to host plasminogen to promote its activation
Sign Up to like & getrecommendations! Published in 2022 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13396
Abstract: Recruitment of plasminogen is an important infection strategy of the human pathogen Streptococcus pneumoniae to invade host tissues. In Streptococcus aureus, triosephosphate isomerase (TPI) has been reported to bind plasminogen. In this study, the TPI of S. pneumoniae… read more here.
Keywords: autolysis binds; triosephosphate isomerase; pneumoniae; plasminogen ... See more keywords
The Total Synthesis of Glycolipids from Streptococcus pneumoniae and a Re‐evaluation of Their Immunological Activity **
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202200361
Abstract: Invariant natural killer (iNK) T cells, Type I iNKTs, are responsible for the production of pro‐inflammatory cytokines which induce a systemic immune response. They are distinctive in possessing an semi‐invariant T‐cell receptor that recognizes glycolipid… read more here.
Keywords: evaluation; activity; total synthesis; receptor ... See more keywords
Identification and molecular characterization of penicillin‐nonsusceptible Streptococcus pneumoniae isolates recovered from invasive infections in a pre‐pneumococcal vaccine era
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Laboratory Analysis"
DOI: 10.1002/jcla.24566
Abstract: Given the significant role of penicillin‐nonsusceptible Streptococcus pneumoniae in inducing severe infectious diseases, identifying serotypes and genotypes that can mediate antimicrobial resistance has become a pillar of treatment strategies. This study aims to determine the… read more here.
Keywords: penicillin; penicillin nonsusceptible; nonsusceptible streptococcus; pneumoniae isolates ... See more keywords
Multicentric Analysis of Erythromycin Resistance Determinants in Invasive Streptococcus pneumoniae; Associated Serotypes and Sequence Types in India.
Sign Up to like & getrecommendations! Published in 2021 at "Current microbiology"
DOI: 10.1007/s00284-021-02594-7
Abstract: Streptococcus pneumoniae is the major cause of childhood pneumonia and related deaths in India. Widespread use of erythromycin for the treatment of pneumonia has led to the emergence of erythromycin resistance. Despite this increase in erythromycin resistance,… read more here.
Keywords: resistance determinants; streptococcus pneumoniae; erythromycin; resistance ... See more keywords
Incidence, mortality, and national costs of hospital admissions for potentially preventable infections in patients with rheumatoid arthritis
Sign Up to like & getrecommendations! Published in 2021 at "Clinical Rheumatology"
DOI: 10.1007/s10067-021-05836-y
Abstract: Rheumatoid arthritis (RA) patients have high infection rates. Streptococcus pneumoniae, herpes zoster (HZV), and influenza are common and potentially preventable causes of morbidity and mortality. Vaccinations have been shown to reduce the rates of these… read more here.
Keywords: potentially preventable; herpes zoster; mortality; streptococcus pneumoniae ... See more keywords
Synthesis of oligosaccharides structurally related to fragments of Streptococcus pneumoniae type 3 capsular polysaccharide
Sign Up to like & getrecommendations! Published in 2017 at "Russian Chemical Bulletin"
DOI: 10.1007/s11172-017-1708-9
Abstract: Abstract3-Aminopropyl glycosides of di-, tri-, and tetrasaccharide structurally related to fragments of Streptococcus pneumoniae type 3 bacteria capsular polysaccharide were synthesized. read more here.
Keywords: pneumoniae type; fragments streptococcus; structurally related; streptococcus pneumoniae ... See more keywords
Gamma-irradiation of Streptococcus pneumoniae for the use as an immunogenic whole cell vaccine
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Microbiology"
DOI: 10.1007/s12275-018-8347-1
Abstract: Streptococcus pneumoniae is a major respiratory pathogen that causes millions of deaths worldwide. Although subunit vaccines formulated with the capsular polysaccharides or their protein conjugates are currently-available, low-cost vaccines with wide serotype coverage still remain… read more here.
Keywords: whole cell; gamma irradiation; pneumoniae; streptococcus pneumoniae ... See more keywords
The virulence of Streptococcus pneumoniae partially depends on dprA
Sign Up to like & getrecommendations! Published in 2017 at "Brazilian Journal of Microbiology"
DOI: 10.1016/j.bjm.2016.10.019
Abstract: Streptococcus pneumoniae is one of the most frequent opportunistic pathogens worldwide. DNA processing protein A (DprA) is an important factor involved in bacterial uptake and DNA integration into bacterial genome, but its role in S.… read more here.
Keywords: strain; virulence; streptococcus pneumoniae; dpra ... See more keywords
Lack of chemokine (C‐C motif) ligand 3 leads to decreased survival and reduced immune response after bacterial meningitis
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DOI: 10.1016/j.cyto.2018.09.001
Abstract: HighlightsCCL3 lack resulted in an ineffective immune response against bacteria in the brain.There is less neutrophils infiltration into the CNS.Decrease of banded neutrophils in the blood of infected CCL3 mice.CCL3‐KO mice showed an decreased cytokine… read more here.
Keywords: meningitis; ccl3; bacterial meningitis; streptococcus pneumoniae ... See more keywords
Nasal colonization with Streptococcus pneumoniae and Staphylococcus aureus among hospitalized patients with laboratory-confirmed influenza.
Sign Up to like & getrecommendations! Published in 2018 at "Diagnostic microbiology and infectious disease"
DOI: 10.1016/j.diagmicrobio.2018.05.007
Abstract: Nasopharyngeal swabs from 148 adult patients with influenza were analyzed by polymerase chain reaction for Staphylococcus aureus and or Streptococcus pneumoniae. We found that patients colonized with S. pneumoniae were younger, had lower oxygen saturations,… read more here.
Keywords: streptococcus pneumoniae; staphylococcus aureus; nasal colonization;