Preclinical safety study of a recombinant Streptococcus pyogenes vaccine formulated with aluminum adjuvant
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.3349
Abstract: A recombinant vaccine composed of a fusion protein formulated with aluminum hydroxide adjuvant is under development for protection against diseases caused by Streptococcus pyogenes. The safety and local reactogenicity of the vaccine was assessed by… read more here.
Keywords: streptococcus pyogenes; formulated aluminum; safety; mice ... See more keywords
Genome‐wide screening of potential RNase Y‐processed mRNAs in the M49 serotype Streptococcus pyogenes NZ131
Sign Up to like & getrecommendations! Published in 2019 at "MicrobiologyOpen"
DOI: 10.1002/mbo3.671
Abstract: RNase Y is a major endoribonuclease in Group A streptococcus (GAS) and other Gram‐positive bacteria. Our previous study showed that RNase Y was involved in mRNA degradation and processing in GAS. We hypothesized that mRNA… read more here.
Keywords: streptococcus pyogenes; mrna processing; rnase processed; rnase ... See more keywords
Detection of Streptococcus pyogenes Virulence Factors.
Sign Up to like & getrecommendations! Published in 2020 at "Methods in molecular biology"
DOI: 10.1007/978-1-0716-0467-0_1
Abstract: Streptococcus pyogenes encodes multiple virulence factors and their presence is often related to the severity of the disease. We designed the system of four low-volume multiplex PCR reactions to detect genes encoding 20 virulence factors:… read more here.
Keywords: streptococcus pyogenes; virulence; virulence factors; detection streptococcus ... See more keywords
Detection of Intracellular Proteins by High-Resolution Immunofluorescence Microscopy in Streptococcus pyogenes.
Sign Up to like & getrecommendations! Published in 2017 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-6673-8_14
Abstract: Immunofluorescence microscopy is an invaluable tool for the study of biological processes at the cellular level. While the localization of surface-exposed antigens can easily be determined using fluorescent antibodies, localization of intracellular antigens requires permeabilization… read more here.
Keywords: streptococcus pyogenes; high resolution; microscopy; immunofluorescence ... See more keywords
[Streptococcus pyogenes infection in paediatrics: from pharyngotonsillitis to invasive infections].
Sign Up to like & getrecommendations! Published in 2018 at "Anales de pediatria"
DOI: 10.1016/j.anpedi.2017.02.011
Abstract: BACKGROUND Streptococcus pyogenes or Group A Streptococci (GAS) cause many infections in infancy. Changes in its epidemiology have been described in recent years, including an increase in invasive infections (iGAS). METHODS A retrospective-descriptive study was… read more here.
Keywords: streptococcus pyogenes; infection paediatrics; invasive infections; gas ... See more keywords
Characterization of a putative maltodextrin-binding protein of Streptococcus pyogenes, SPs0871 and the development of a VHH inhibitor.
Sign Up to like & getrecommendations! Published in 2021 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2021.05.056
Abstract: Streptococcus pyogenes causes a wide range of human infections. Currently, antibiotics are the main treatment for S. pyogenes infection, but serious anti-microbial resistance requires alternative treatment options. To develop a novel strategy for treatment, we physicochemically… read more here.
Keywords: streptococcus pyogenes; development vhh; vhh; binding protein ... See more keywords
Streptococcus pyogenes upregulates arginine catabolism to exert its pathogenesis on the skin surface.
Sign Up to like & getrecommendations! Published in 2021 at "Cell reports"
DOI: 10.1016/j.celrep.2021.108924
Abstract: The arginine deiminase (ADI) pathway has been found in many kinds of bacteria and functions to supplement energy production and provide protection against acid stress. The Streptococcus pyogenes ADI pathway is upregulated upon exposure to… read more here.
Keywords: arginine catabolism; streptococcus pyogenes; adi pathway; pathogenesis ... See more keywords
A Host Proteome Atlas of Streptococcus pyogenes Infection.
Sign Up to like & getrecommendations! Published in 2018 at "Cell systems"
DOI: 10.1016/j.cels.2018.05.003
Abstract: Multiplex quantitative proteomics analysis of mice infected with Group A Streptococcus reveals organ-specific biomarkers of infection. read more here.
Keywords: streptococcus pyogenes; atlas streptococcus; infection; proteome atlas ... See more keywords
Scarlet Fever Epidemic in China Caused by Streptococcus pyogenes Serotype M12: Epidemiologic and Molecular Analysis
Sign Up to like & getrecommendations! Published in 2018 at "EBioMedicine"
DOI: 10.1016/j.ebiom.2018.01.010
Abstract: From 2011, Hong Kong and mainland China have witnessed a sharp increase in reported cases, with subsequent reports of epidemic scarlet fever in North Asia and the United Kingdom. Here we examine epidemiological data and… read more here.
Keywords: streptococcus pyogenes; scarlet; scarlet fever; china ... See more keywords
Acanthamoeba castellanii interactions with Streptococcus pneumoniae and Streptococcus pyogenes.
Sign Up to like & getrecommendations! Published in 2017 at "Experimental parasitology"
DOI: 10.1016/j.exppara.2017.08.005
Abstract: Among the genus Streptococcus, S. pyogenes and S. pneumoniae are the major causes of pharyngitis, impetigo, pneumonia and meningitis in humans. Streptococcus spp. are facultative anaerobes that are nutritionally fastidious, yet survive in the environment and target… read more here.
Keywords: streptococcus pyogenes; pyogenes pneumoniae; acanthamoeba castellanii; interactions streptococcus ... See more keywords
Lemierre's syndrome caused by Streptococcus pyogenes in an elderly woman
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Vascular Surgery Cases and Innovative Techniques"
DOI: 10.1016/j.jvscit.2019.11.007
Abstract: Lemierre's syndrome is characterized by septic thrombophlebitis of the internal jugular vein. It typically presents in healthy adolescents or young adults, usually preceded by an oropharyngeal infection, with the most common offending pathogen being Fusobacterium… read more here.
Keywords: lemierre syndrome; caused streptococcus; streptococcus pyogenes; elderly woman ... See more keywords