Discovery of gas vesicles in Streptomyces sp. CB03234-S and potential effects of gas vesicle gene overexpression on morphological and metabolic changes in streptomycetes
Sign Up to like & getrecommendations! Published in 2019 at "Applied Microbiology and Biotechnology"
DOI: 10.1007/s00253-019-09891-z
Abstract: Gas vesicles are usually found in aquatic microbes to help against adverse growth conditions and also present applied potentials in various biotechnological areas. Although gvp genes encoding gas vesicle proteins are occurred in many bacteria,… read more here.
Keywords: gas vesicles; gas; potential effects; gas vesicle ... See more keywords
Combinatorial metabolic engineering of Streptomyces sp. CB03234-S for the enhanced production of anthraquinone-fused enediyne tiancimycins
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DOI: 10.1186/s12934-024-02399-w
Abstract: Background Anthraquinone-fused enediynes (AFEs) are excellent payloads for antibody-drug conjugates (ADCs). The yields of AFEs in the original bacterial hosts are extremely low. Multiple traditional methods had been adopted to enhance the production of the… read more here.
Keywords: combinatorial metabolic; anthraquinone fused; streptomyces cb03234; metabolic engineering ... See more keywords
Genomic Comparisons Revealed the Key Genotypes of Streptomyces sp. CB03234-GS26 to Optimize Its Growth and Relevant Production of Tiancimycins
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DOI: 10.3390/bioengineering11111128
Abstract: Strain robustness and titer improvement are major challenges faced in the industrial development of natural products from Streptomyces. Tiancimycins (TNMs) produced by Streptomyces sp. CB03234 are promising anticancer payloads for antibody-drug conjugates, but further development… read more here.
Keywords: streptomyces cb03234; comparisons revealed; cb03234 gs26; genomic comparisons ... See more keywords