Approaches towards the enhanced production of Rapamycin by Streptomyces hygroscopicus MTCC 4003 through mutagenesis and optimization of process parameters by Taguchi orthogonal array methodology
Sign Up to like & getrecommendations! Published in 2017 at "World Journal of Microbiology and Biotechnology"
DOI: 10.1007/s11274-017-2260-3
Abstract: The present research was conducted to define the approaches for enhanced production of rapamycin (Rap) by Streptomyces hygroscopicus microbial type culture collection (MTCC) 4003. Both physical mutagenesis by ultraviolet ray (UV) and chemical mutagenesis by… read more here.
Keywords: streptomyces hygroscopicus; mutagenesis; methodology; production rapamycin ... See more keywords
Specific mutation of transglutaminase gene from Streptomyces hygroscopicus H197 and characterization of microbial transglutaminase
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Biosciences"
DOI: 10.1007/s12038-017-9707-4
Abstract: Abstract Microbial transglutaminase (MTG) gene (mtg) from Streptomyces hygroscopicus H197 strain was cloned by PCR and mutated by deleting a specific 84 bp fragment using overlapping extension PCR. The mutant MTG and the wild MTG genes… read more here.
Keywords: streptomyces hygroscopicus; transglutaminase; hygroscopicus h197; mtg ... See more keywords
Physiological, biochemical and proteomic insight into the response system of Streptomyces hygroscopicus OsiSh-2 to rice blast fungus toxins
Sign Up to like & getrecommendations! Published in 2021 at "Applied Soil Ecology"
DOI: 10.1016/j.apsoil.2021.104058
Abstract: Abstract Magnaporthe oryzae is a major hazard to the growth and yield of rice and other graminaceous crops. The rice endophyte Streptomyces hygroscopicus OsiSh-2 has been reported to have a strong antagonistic effect on M.… read more here.
Keywords: rice; response; hygroscopicus osish; streptomyces hygroscopicus ... See more keywords
Streptomyces hygroscopicus UFPEDA 3370: A valuable source of the potent cytotoxic agent nigericin and its evaluation against human colorectal cancer cells.
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DOI: 10.1016/j.cbi.2020.109316
Abstract: Streptomyces hygroscopicus UFPEDA 3370 was fermented in submerged cultivation and the biomass extract was partitioned, obtaining a fraction purified named EB1. After purification of EB1 fraction, nigericin free acid was obtained and identified. Nigericin presented… read more here.
Keywords: streptomyces hygroscopicus; hygroscopicus ufpeda; 3370 valuable; cytotoxic ... See more keywords
Enhancement of ascomycin production via a combination of atmospheric and room temperature plasma mutagenesis in Streptomyces hygroscopicus and medium optimization
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DOI: 10.1186/s13568-019-0749-x
Abstract: Ascomycin, a key intermediate for chemical synthesis of immunosuppressive drug pimecrolimus, is produced by Streptomyces hygroscopicus var. ascomyceticus. In order to improve the strain production, the original S. hygroscopicus ATCC 14891 strain was treated here… read more here.
Keywords: streptomyces hygroscopicus; production; ascomycin production; room temperature ... See more keywords
Fractions 14 and 36K of Metabolite Extract Streptomyces hygroscopicus subsp. Hygroscopicus Have Antimalarial Activities Against Plasmodium berghei in vitro
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DOI: 10.2147/idr.s400538
Abstract: Purpose The study was conducted to investigate the effectivity and the cytotoxicity of fractions 14 and 36K of metabolite extract of Streptomyces hygroscopicus subsp. Hygroscopicus as an antimalarial compounds against Plasmodium berghei in vitro. Methods… read more here.
Keywords: streptomyces hygroscopicus; subsp hygroscopicus; hygroscopicus subsp; plasmodium berghei ... See more keywords
Overexpression and Biochemical Properties of a GH46 Chitosanase From Marine Streptomyces hygroscopicus R1 Suitable for Chitosan Oligosaccharides Preparation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.816845
Abstract: Due to the various biological activities of chitosan oligosaccharides (COSs), they have great potential value for use in many areas. Chitosanase plays an important role in enzymatic preparation of COSs. Herein, a gene encoding a… read more here.
Keywords: marine streptomyces; chitosan oligosaccharides; streptomyces hygroscopicus; chitosanase ... See more keywords
New Strategies in Optimization of Rapamycin Production by Streptomyces hygroscopicus ATCC 29253
Sign Up to like & getrecommendations! Published in 2019 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2019.00722.4
Abstract: The challenge of finding out new methodologies and strategies for improving production of the multifunction highly potent medication “rapamycin by Streptomyces hygroscopicus ATCC 29253 was adopted in the current study. Nano-sizing of soy meal, as… read more here.
Keywords: rapamycin production; hygroscopicus atcc; streptomyces hygroscopicus; production ... See more keywords