Schiff Bases of Pioglitazone Provide Better Antidiabetic and Potent Antioxidant Effect in a Streptozotocin–Nicotinamide-Induced Diabetic Rodent Model
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DOI: 10.1021/acsomega.0c06064
Abstract: Pioglitazone is a Food and Drug Administration-approved thiazolidinedione (TZD) derivative and peroxisome proliferator-activated receptor gamma (PPARγ) agonist and used for the treatment of diabetes mellitus (DM). However, this drug is still associated with many adverse… read more here.
Keywords: bases pioglitazone; schiff bases; pioglitazone; streptozotocin nicotinamide ... See more keywords
Metabolic Alterations in Streptozotocin–nicotinamide-induced Diabetic Rats Treated with Muntingia calabura Extract via 1 H-NMR-based Metabolomics
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DOI: 10.1055/a-2053-0950
Abstract: Abstract Diabetes mellitus (DM) is a metabolic endocrine disorder caused by decreased insulin concentration or poor insulin response. Muntingia calabura (MC) has been used traditionally to reduce blood glucose levels. This study aims to support… read more here.
Keywords: streptozotocin nicotinamide; diabetic rats; induced diabetic; muntingia calabura ... See more keywords