Negative control of cytokinesis by stress-activated MAPK signaling.
Sign Up to like & getrecommendations! Published in 2021 at "Current genetics"
DOI: 10.1007/s00294-021-01155-6
Abstract: Mitogen-activated protein kinase (MAPK) signalling pathways regulate multiple cellular functions in eukaryotic organisms in response to environmental cues, including the dynamic remodeling of the actin cytoskeleton. The fission yeast S. pombe is an optimal model… read more here.
Keywords: stress activated; cytokinesis; car; negative control ... See more keywords
Stress-Activated NRF2-MDM2 Cascade Controls Neoplastic Progression in Pancreas.
Sign Up to like & getrecommendations! Published in 2017 at "Cancer cell"
DOI: 10.1016/j.ccell.2017.10.011
Abstract: Despite expression of oncogenic KRAS, premalignant pancreatic intraepithelial neoplasia 1 (PanIN1) lesions rarely become fully malignant pancreatic ductal adenocarcinoma (PDAC). The molecular mechanisms through which established risk factors, such as chronic pancreatitis, acinar cell damage,… read more here.
Keywords: stress activated; pdac; mdm2; neoplastic progression ... See more keywords
Stress-Activated Protein Kinases in Human Fungal Pathogens
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Cellular and Infection Microbiology"
DOI: 10.3389/fcimb.2019.00261
Abstract: The ability of fungal pathogens to survive hostile environments within the host depends on rapid and robust stress responses. Stress-activated protein kinase (SAPK) pathways are conserved MAPK signaling modules that promote stress adaptation in all… read more here.
Keywords: sapk pathways; sapk; stress activated; fungal pathogens ... See more keywords
Characterizing and TRAPing a Social Stress-Activated Neuronal Ensemble in the Ventral Tegmental Area
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Behavioral Neuroscience"
DOI: 10.3389/fnbeh.2022.936087
Abstract: Social stress is a major contributor to neuropsychiatric issues such as depression, substance abuse and eating disorders. The ventral tegmental area (VTA) is involved in the effects of stress on cognitive and emotional processes perturbed… read more here.
Keywords: stress; tegmental area; social stress; ventral tegmental ... See more keywords
Stress Activated MAP Kinases and Cyclin-Dependent Kinase 5 Mediate Nuclear Translocation of Nrf2 via Hsp90α-Pin1-Dynein Motor Transport Machinery
Sign Up to like & getrecommendations! Published in 2023 at "Antioxidants"
DOI: 10.3390/antiox12020274
Abstract: Non-lethal low levels of oxidative stress leads to rapid activation of the transcription factor nuclear factor-E2-related factor 2 (Nrf2), which upregulates the expression of genes important for detoxification, glutathione synthesis, and defense against oxidative damage.… read more here.
Keywords: nrf2; hsp90; pin1; activated map ... See more keywords
Regulation of Stress-Activated Kinases in Response to Tacaribe Virus Infection and Its Implications for Viral Replication
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14092018
Abstract: Arenaviruses include important zoonotic pathogens that cause hemorrhagic fever (e.g., Junín virus; JUNV) as well as other viruses that are closely related but apathogenic (e.g., Tacaribe virus; TCRV). We have found that, while TCRV and… read more here.
Keywords: apoptosis; tacaribe virus; virus; activation ... See more keywords