Oxidative Stress in Cancer Therapy: Friend or Enemy?
Sign Up to like & getrecommendations! Published in 2022 at "ChemBioChem"
DOI: 10.1002/cbic.202100641
Abstract: Excessive cellular oxidative stress is widely perceived as a key factor in pathophysiological conditions and cancer development. Healthy cells use several mechanisms to maintain intracellular levels of reactive oxygen species (ROS) and overall redox homeostasis… read more here.
Keywords: stress cancer; stress; oxidative stress; cancer therapy ... See more keywords
MicroRNA and ER stress in cancer.
Sign Up to like & getrecommendations! Published in 2021 at "Seminars in cancer biology"
DOI: 10.1016/j.semcancer.2020.12.025
Abstract: The development of biological technologies in genomics, proteomics, and bioinformatics has led to the identification and characterization of the complete set of coding genes and their roles in various cellular pathways in cancer. Nevertheless, the… read more here.
Keywords: microrna stress; cellular pathways; stress; noncoding rnas ... See more keywords
ER stress of cancer cell SCC25 induces LOX-1-expressed immunosuppressive neutrophils
Sign Up to like & getrecommendations! Published in 2019 at "Annals of Oncology"
DOI: 10.1093/annonc/mdz452.025
Abstract: Abstract Background Immunosuppressive neutrophils with surface expression of lectin-like oxidized low-density lipoprotein receptor-1 (LOX-1) existed at both tumor sites and blood in patients with head and neck squamous cell carcinoma (HNSCC). Their immunosuppressive activities were… read more here.
Keywords: cell; scc25; stress; immunosuppressive neutrophils ... See more keywords
Surgical stress and cancer progression: the twisted tango
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DOI: 10.1186/s12943-019-1058-3
Abstract: Surgical resection is an important avenue for cancer treatment, which, in most cases, can effectively alleviate the patient symptoms. However, accumulating evidence has documented that surgical resection potentially enhances metastatic seeding of tumor cells. In… read more here.
Keywords: progression twisted; surgical stress; stress; cancer progression ... See more keywords
Stress and cancer: The mechanisms of immune dysregulation and management
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.1032294
Abstract: Advances in the understanding of psychoneuroimmunology in the past decade have emphasized the notion that stress and cancer are interlinked closely. Durable chronic stress accelerated tumorigenesis and progression, which is unfavorable for clinical outcomes of… read more here.
Keywords: stress cancer; stress; cancer mechanisms; management ... See more keywords
Interplay between stress and cancer—A focus on inflammation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2023.1119095
Abstract: Stress is an integral part of life. While acute responses to stress are generally regarded as beneficial in dealing with immediate threats, chronic exposure to threatening stimuli exerts deleterious effects and can be either a… read more here.
Keywords: stress cancer; stress; inflammation; interplay stress ... See more keywords
Oxidative Stress and Cancer Heterogeneity Orchestrate NRF2 Roles Relevant for Therapy Response
Sign Up to like & getrecommendations! Published in 2022 at "Molecules"
DOI: 10.3390/molecules27051468
Abstract: Oxidative stress and its end-products, such as 4-hydroxynonenal (HNE), initiate activation of the Nuclear Factor Erythroid 2-Related Factor 2 (NRF2)/Kelch Like ECH Associated Protein 1 (KEAP1) signaling pathway that plays a crucial role in the… read more here.
Keywords: stress cancer; oxidative stress; therapy; response ... See more keywords