High sucrose low copper diet in pregnant diabetic rats induces transient oxidative stress, hypoxia, and apoptosis in the offspring's liver.
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DOI: 10.1002/bdr2.1341
Abstract: BACKGROUND Hyperglycemia-related oxidative stress and hypoxia are important mechanisms responsible for diabetes-induced embryopathy and other complications. High sucrose low copper diet (HSD), but not regular diet (RD), induces type 2 diabetes in the inbred Cohen… read more here.
Keywords: apoptosis; high sucrose; stress hypoxia; sucrose low ... See more keywords
Epigenetic enzymes influenced by oxidative stress and hypoxia mimetic in osteoblasts are differentially expressed in patients with osteoporosis and osteoarthritis
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DOI: 10.1038/s41598-018-34255-4
Abstract: Epigenetic mechanisms including posttranslational histone modifications and DNA methylation are emerging as important determinants of bone homeostasis. With our case-control study we aimed to identify which chromatin-modifying enzymes could be involved in the pathology of… read more here.
Keywords: stress hypoxia; stress; osteoporosis osteoarthritis; oxidative stress ... See more keywords