Scutellarin alleviates blood‐retina‐barrier oxidative stress injury initiated by activated microglia cells during the development of diabetic retinopathy
Sign Up to like & getrecommendations! Published in 2019 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.11.011
Abstract: &NA; The breakdown of blood‐retinal barrier (BRB) is an early and typical event during the development of diabetic retinopathy (DR). Scutellarin (SC) is a natural flavonoid. This study aims to investigate the protection of SC… read more here.
Keywords: microglia cells; stress injury; development; oxidative stress ... See more keywords
Microfluidic method reduces osmotic stress injury to oocytes during cryoprotectant addition and removal processes in porcine oocytes.
Sign Up to like & getrecommendations! Published in 2019 at "Cryobiology"
DOI: 10.1016/j.cryobiol.2019.08.005
Abstract: Oocyte cryopreservation is an important technology in assisted reproduction and fertility preservation. However, the developmental potential of cryopreserved oocyte remains poor. Osmotic stress injury (OSI) during cryoprotectants (CPAs) loading and unloading steps has critical impact… read more here.
Keywords: stress injury; porcine oocytes; step wise; osmotic stress ... See more keywords
Salvianolic acid B attenuates experimental pulmonary inflammation by protecting endothelial cells against oxidative stress injury
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Pharmacology"
DOI: 10.1016/j.ejphar.2018.09.030
Abstract: ABSTRACT Endothelial cell injury and subsequent inflammation play pivotal roles in the pathogenesis of pulmonary fibrosis, a progressive and fatal disorder. We found previously that salvianolic acid B (SAB) attenuated experimental pulmonary fibrosis. Pulmonary fibrosis… read more here.
Keywords: cells oxidative; stress injury; pulmonary fibrosis; endothelial cells ... See more keywords
Effect of (m)VD-hemopressin against Aβ1-42-induced oxidative stress and apoptosis in mouse hippocampal neurons
Sign Up to like & getrecommendations! Published in 2020 at "Peptides"
DOI: 10.1016/j.peptides.2019.170185
Abstract: Alzheimer's disease (AD) is a serious neurodegenerative disease. Senile plaques (SPs) composed of amyloid-β (Aβ) are typical features of AD. Aβ plays a key role in the disease and has the ability to induce other… read more here.
Keywords: stress injury; hippocampal neurons; apoptosis; stress ... See more keywords
Overexpression of miR‐22 attenuates oxidative stress injury in diabetic cardiomyopathy via Sirt 1
Sign Up to like & getrecommendations! Published in 2018 at "Cardiovascular Therapeutics"
DOI: 10.1111/1755-5922.12318
Abstract: BACKGROUND/AIMS Oxidative stress injury is believed to be important in diabetic cardiomyopathy. Recent evidence indicates that miR-22 plays an important role in various cardiovascular diseases, but the protective role of miR-22 in diabetic cardiomyopathy remains… read more here.
Keywords: oxidative stress; stress injury; mir; sirt ... See more keywords
Lysophosphatidylcholine Offsets the Protective Effects of Bone Marrow Mesenchymal Stem Cells on Inflammatory Response and Oxidative Stress Injury of Retinal Endothelial Cells via TLR4/NF-κB Signaling
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Immunology Research"
DOI: 10.1155/2021/2389029
Abstract: Diabetic retinopathy (DR), as a major cause of blindness worldwide, is one common complication of diabetes mellitus. Inflammatory response and oxidative stress injury of endothelial cells play significant roles in the pathogenesis of DR. The… read more here.
Keywords: response oxidative; stress injury; inflammatory response; oxidative stress ... See more keywords
Butein Inhibits Oxidative Stress Injury in Rats with Chronic Heart Failure via ERK/Nrf2 Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Cardiovascular Therapeutics"
DOI: 10.1155/2022/8684014
Abstract: Background Chronic heart failure (CHF) is a serious heart disease resulting from cardiac dysfunction. Oxidative stress is an important factor in aging and disease. Butein, however, has antioxidant properties. To determine the effect of butein… read more here.
Keywords: stress injury; nrf2 signaling; oxidative stress; heart ... See more keywords
MicroRNA miR-34a-5p inhibition restrains oxidative stress injury of macrophages by targeting MDM4
Sign Up to like & getrecommendations! Published in 2022 at "Vascular"
DOI: 10.1177/17085381211069447
Abstract: Objective Atherosclerosis is a chronic cardiovascular disease associated with oxidative stress damage, which is caused by excessive oxidation of low-density lipoprotein (ox-LDL). The role of microRNA miR-34a-5p on oxidative stress in ox-LDL–treated macrophages was investigated… read more here.
Keywords: mdm4; stress injury; oxidative stress; microrna mir ... See more keywords
AP2a-Mediated Upregulation of miR-125a-5p Ameliorates Radiation-Induced Oxidative Stress Injury via BRD4/Nrf2/HO-1 Signaling
Sign Up to like & getrecommendations! Published in 2022 at "Radiation Research"
DOI: 10.1667/rade-22-00107.1
Abstract: Radiation therapy is widely used to restrain tumor progression, but it is always accompanied by damage to healthy tissues. We aimed to probe the impact and mechanism of activator protein 2a (AP2a) and miR-125a-5p in… read more here.
Keywords: mir 125a; oxidative stress; radiation; brd4 ... See more keywords
ELA-11 protects the heart against oxidative stress injury induced apoptosis through ERK/MAPK and PI3K/AKT signaling pathways
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.873614
Abstract: Increasing evidence revealed that apoptosis and oxidative stress injury were associated with the pathophysiology of doxorubicin (DOX)-induced myocardial injury. ELABELA (ELA) is a newly identified peptide with 32 amino acids, can reduce hypertension with exogenous… read more here.
Keywords: stress injury; stress; oxidative stress; induced apoptosis ... See more keywords
(±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) Benzoate Protects Against Oxidative Stress Injury in PC12 Cells Exposed to H2O2 Through Activation of Nrf2 Pathway
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.943111
Abstract: Background: Oxidative stress is associated with the pathogenesis of ischemic stroke (±)-5-bromo-2-(5-fluoro-1-hydroxyamyl) benzoate (BFB) is a novel compound modified by dl-3-n-butylphthalide (NBP). Here, we hypothesized that BFB may protect the PC12 cells against H2O2-induced oxidative… read more here.
Keywords: oxidative stress; bfb; nrf2 pathway; pc12 cells ... See more keywords