ER Stress Promotes Inflammation through Re-wIREd Macrophages in Obesity.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular cell"
DOI: 10.1016/j.molcel.2017.05.037
Abstract: A new mechanism linking ER dysfunction to metabolic inflammation is discovered in a recent study by Shan et al. (2017), which demonstrated ER stress-induced rewiring of adipose tissue macrophage polarization by IRE1α activation, leading to impaired… read more here.
Keywords: wired macrophages; stress promotes; inflammation; inflammation wired ... See more keywords
Neuronal Oxidative Stress Promotes α-Synuclein Aggregation In Vivo
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DOI: 10.3390/antiox11122466
Abstract: Both genetic and environmental factors increase risk for Parkinson’s disease. Many of the known genetic factors influence α-synuclein aggregation or degradation, whereas most of the identified environmental factors produce oxidative stress. Studies using in vitro… read more here.
Keywords: stress; synuclein aggregation; oxidative stress; neuronal oxidative ... See more keywords