Pharmacological interventions for stress ulcer prophylaxis in critically ill patients: a mixed treatment comparison network meta-analysis and a recursive cumulative meta-analysis
Sign Up to like & getrecommendations! Published in 2018 at "Expert Opinion on Pharmacotherapy"
DOI: 10.1080/14656566.2017.1419187
Abstract: ABSTRACT Background: Proton pump inhibitors (PPI), histamine-2 receptor antagonists (H2RA), sucralfate and antacids are the commonly administered agents for stress ulcer prophylaxis (SUP) in critically ill patients. The authors of this paper have conducted a… read more here.
Keywords: ill patients; critically ill; meta; stress ulcer ... See more keywords
Stress Ulcer Prophylaxis in Critically Ill Children: A Multicenter Observational Study
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DOI: 10.1097/pcc.0000000000002202
Abstract: Objective: To describe current stress ulcer prophylaxis practice in Canadian PICUs. Design: Multicenter cohort study. We defined stress ulcer prophylaxis as the use of a proton-pump inhibitor, histamine-2 receptor antagonist, or sucralfate within the first… read more here.
Keywords: stress ulcer; prophylaxis; ulcer prophylaxis; study ... See more keywords
Stress ulcer prophylaxis in adult intensive care unit patients – a protocol for a systematic review
Sign Up to like & getrecommendations! Published in 2018 at "Acta Anaesthesiologica Scandinavica"
DOI: 10.1111/aas.13109
Abstract: In the intensive care unit (ICU), stress ulcer prophylaxis with proton pump inhibitors or histamine‐2‐receptor antagonists is standard of care although gastrointestinal bleeding remains uncommon. It remains unknown whether its use is associated with benefits… read more here.
Keywords: care unit; intensive care; stress ulcer; ulcer prophylaxis ... See more keywords
Stress Ulcer Prophylaxis in Critically Ill Adult Patients with Sepsis at Risk of Gastrointestinal Bleeding: A Retrospective Cohort Study.
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DOI: 10.1111/imj.15598
Abstract: BACKGROUND The Surviving Sepsis Campaign Guidelines recommend stress ulcer prophylaxis (SUP) for patients with sepsis who have gastrointestinal (GI) bleeding risks, however, the effect of SUP has not been specially studied in these patients. AIMS… read more here.
Keywords: gastrointestinal bleeding; critically ill; stress ulcer; ulcer prophylaxis ... See more keywords
Effects of stress ulcer prophylaxis in adult ICU patients receiving renal replacement therapy (Sup-Icu RENal, SIREN): Study protocol for a pre-planned observational study
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DOI: 10.1186/s13063-017-2408-3
Abstract: BackgroundProton pump inhibitors are often used in critically ill patients to prevent gastrointestinal bleeding despite limited evidence for benefit. Patients with acute kidney injury requiring renal replacement therapy (RRT) are at high risk of gastrointestinal… read more here.
Keywords: adult; study; icu; stress ulcer ... See more keywords
Pediatric intensive care stress ulcer prevention (PIC-UP): a protocol for a pilot randomized trial
Sign Up to like & getrecommendations! Published in 2017 at "Pilot and Feasibility Studies"
DOI: 10.1186/s40814-017-0142-y
Abstract: BackgroundDespite sparse pediatric data on effectiveness, the majority of critically ill children receive medications to prevent gastrointestinal (GI) bleeding. Stress ulcer prophylaxis may have unintended consequences—increasing the risk of nosocomial infections—which may be more serious… read more here.
Keywords: pilot; trial; stress ulcer; ulcer prophylaxis ... See more keywords
Stress Ulcer Prophylaxis for Critical Asthma.
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DOI: 10.1542/peds.2021-054527
Abstract: BACKGROUND Children hospitalized for critical asthma (CA) in the pediatric ICU (PICU) are commonly prescribed stress ulcer prophylaxis (SUP) to mitigate risk of gastrointestinal (GI) bleeding. We sought to describe trends for SUP prescribing and… read more here.
Keywords: stress ulcer; critical asthma; ulcer prophylaxis; sup ... See more keywords
CYP2C19 Gene Profiling as a Tool for Personalized Stress Ulcer Prophylaxis With Proton Pump Inhibitors in Critically Ill Patients - Recommendations Proposal
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Medicine"
DOI: 10.3389/fmed.2022.854280
Abstract: To this date, there are no recommendations for personalized stress ulcer prophylaxis (SUP) in critical care that would take the patient's individual genetic predispositions into account. Of drugs used for this purpose, proton pump inhibitors… read more here.
Keywords: pump inhibitors; proton pump; stress ulcer; cyp2c19 gene ... See more keywords