Crosstalk between cytotoxic CD8+ T cells and stressed cardiomyocytes triggers development of interstitial cardiac fibrosis in hypertensive mouse hearts
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DOI: 10.3389/fimmu.2022.1040233
Abstract: Graphical Abstract Cardiac fibrosis developed from fibrotic remodelling due to hypertension leads to heart failure. Immune cells are abundantly accumulated in fibrotic regions, but exact mechanisms how they contributed to cardiac fibrosis are not clear.… read more here.
Keywords: stressed cardiomyocytes; cardiac fibrosis; cd8 cells; rae ... See more keywords