Inflammatory β-Cell Stress and Immune Surveillance in Type 1 Diabetes.
Sign Up to like & getrecommendations! Published in 2024 at "Cold Spring Harbor perspectives in medicine"
DOI: 10.1101/cshperspect.a041605
Abstract: Recent years have seen increased recognition for the role of β-cell stress as a contributing factor to the autoimmune destruction process that ultimately results in symptomatic type 1 diabetes (T1D). Preclinical studies have discovered a… read more here.
Keywords: cell stress; stressed cells; immune surveillance; cell ... See more keywords
Stressed β-cells contribute to loss of peri-islet extracellular matrix in type 1 diabetes
Sign Up to like & getrecommendations! Published in 2025 at "Frontiers in Endocrinology"
DOI: 10.3389/fendo.2025.1675043
Abstract: Introduction Type 1 diabetes (T1D) is characterized by the immune-mediated destruction of insulin-producing β-cells in pancreatic islets. The peri-islet extracellular matrix (ECM) is a complex protein barrier that is lost in T1D, in part due… read more here.
Keywords: stressed cells; loss; type diabetes; t1d ... See more keywords