Dipeptide Mimetic of the Brain-derived Neurotrophic Factor Prevents Impairments of Neurogenesis in Stressed Mice
Sign Up to like & getrecommendations! Published in 2017 at "Bulletin of Experimental Biology and Medicine"
DOI: 10.1007/s10517-017-3638-9
Abstract: Brain-derived neurotrophic factor (BDNF) plays the central role in the mechanisms of regulation of neurogenesis and neuroplasticity. Impairment of these mechanisms is considered as one of the main etiological factors of depression. Dimeric dipeptide mimetic… read more here.
Keywords: brain derived; derived neurotrophic; gsb 106; stressed mice ... See more keywords
Involvement of protein kinase C beta1-serotonin transporter system dysfunction in emotional behaviors in stressed mice
Sign Up to like & getrecommendations! Published in 2020 at "Neurochemistry International"
DOI: 10.1016/j.neuint.2020.104826
Abstract: Selective serotonin reuptake inhibitors are the first-line antidepressants for treating major depressive and post-traumatic stress disorders. These inhibitors directly bind to the serotonin transporter (SERT). Protein kinase C (PKC) is a key regulator of SERT… read more here.
Keywords: serotonin transporter; sert; stressed mice; stress ... See more keywords
Rubiscolin-6, a δ-Opioid Peptide from Spinach RuBisCO, Exerts Antidepressant-Like Effect in Restraint-Stressed Mice.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of nutritional science and vitaminology"
DOI: 10.3177/jnsv.65.202
Abstract: Rubiscolin-6 (Tyr-Pro-Leu-Asp-Leu-Phe) is produced by a pepsin digest of spinach d-ribulose-1,5-bisphosphate carboxylase/oxygenase (RuBisCO) and known to act as an agonist on δ-opioid receptor. Here, we showed that administration of rubiscolin-6 reduced immobility time in the… read more here.
Keywords: restraint stressed; rubiscolin; like effect; stressed mice ... See more keywords
Implications of gut microbiota dysbiosis and fecal metabolite changes in psychologically stressed mice
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2023.1124454
Abstract: Introduction Psychological stress can induce affective disorders. Gut microbiota plays a vital role in emotional function regulation; however, the association between gut microbiota and psychological stress is poorly understood. We investigated effects of psychological stress… read more here.
Keywords: psychological stress; stressed mice; gut microbiota;
Spontaneous Activity of CB2 Receptors Attenuates Stress-Induced Behavioral and Neuroplastic Deficits in Male Mice
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2021.805758
Abstract: The monoaminergic theory of depression/anxiety disorders cannot fully explain the behavioral and neuroplastic changes observed after ADs chronic treatment. Endocannabinoid system, which comprises CB2 receptors, has been associated with the chronic effects of these drugs,… read more here.
Keywords: stress; cb2; behavioral neuroplastic; cb2 receptors ... See more keywords