PARP1 proximity proteomics reveals interaction partners at stressed replication forks
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DOI: 10.1093/nar/gkac948
Abstract: Abstract PARP1 mediates poly-ADP-ribosylation of proteins on chromatin in response to different types of DNA lesions. PARP inhibitors are used for the treatment of BRCA1/2-deficient breast, ovarian, and prostate cancer. Loss of DNA replication fork… read more here.
Keywords: replication; proximity proteomics; stressed replication; parp1 ... See more keywords