Intact striatal dopaminergic modulation of reward learning and daily-life reward-oriented behavior in first-degree relatives of individuals with psychotic disorder
Sign Up to like & getrecommendations! Published in 2017 at "Psychological Medicine"
DOI: 10.1017/s0033291717003476
Abstract: Background Abnormalities in reward learning in psychotic disorders have been proposed to be linked to dysregulated subcortical dopaminergic (DA) neurotransmission, which in turn is a suspected mechanism for predisposition to psychosis. We therefore explored the… read more here.
Keywords: reward oriented; dopaminergic modulation; striatal dopaminergic; oriented behavior ... See more keywords
Apathy Reflects Extra-Striatal Dopaminergic Degeneration in de novo Parkinson's Disease.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Parkinson's disease"
DOI: 10.3233/jpd-223223
Abstract: BACKGROUND Apathy represents a core neuropsychiatric symptom in Parkinson's disease (PD). As there is currently no established effective treatment for apathy in PD, further investigating the biological origin of this symptom is needed to design… read more here.
Keywords: extra striatal; dopaminergic degeneration; parkinson disease; striatal dopaminergic ... See more keywords
Striatal dopaminergic lesions contributed to the disease severity in progressive supranuclear palsy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Aging Neuroscience"
DOI: 10.3389/fnagi.2022.998255
Abstract: Background Reduced dopamine transporter (DAT) binding in the striatum has been reported in patients with progressive supranuclear palsy (PSP). However, the relationship between striatal dopaminergic lesions and the disease severity of PSP remains to be… read more here.
Keywords: severity psp; dopaminergic lesions; striatal dopaminergic; severity ... See more keywords