Striatal synaptic bioenergetic and autophagic decline in premotor experimental parkinsonism
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DOI: 10.1093/brain/awac087
Abstract: Abstract Synaptic impairment might precede neuronal degeneration in Parkinson’s disease. However, the intimate mechanisms altering synaptic function by the accumulation of presynaptic α-synuclein in striatal dopaminergic terminals before dopaminergic death occurs, have not been elucidated.… read more here.
Keywords: striatal synaptic; synaptic bioenergetic; dopaminergic terminals; death ... See more keywords