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   Articles with "stringent response" as a keyword



The stringent response of marine bacteria – assessment of (p)ppGpp accumulation upon stress conditions

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recommendations! Published in 2019 at "Journal of Applied Genetics"

DOI: 10.1007/s13353-019-00531-w

Abstract: Microorganisms are particularly adapted to alterations in their environment. One of the global regulatory mechanisms involved in these adaptations is the stringent response. The unusual nucleotides, guanosine penta and tetraphosphates, (p)ppGpp act as alarmones of… read more here.

Keywords: marine bacteria; stringent response; ppgpp accumulation; response ... See more keywords

The stringent response factor, RelA, positively regulates T6SS4 expression through the RovM/RovA pathway in Yersinia pseudotuberculosis.

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recommendations! Published in 2019 at "Microbiological research"

DOI: 10.1016/j.micres.2018.12.002

Abstract: The type VI secretion system (T6SS) is a versatile molecular machinery widely distributed in Gram-negative bacteria. The activity of the T6SS is tightly regulated by various mechanisms, including quorum sensing (QS), iron concentration, and transcriptional… read more here.

Keywords: response; stringent response; rela positively; expression ... See more keywords
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Stringent response in bacteria and plants under infection.

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recommendations! Published in 2021 at "Phytopathology"

DOI: 10.1094/phyto-11-20-0510-r

Abstract: Stringent response (SR), a primary stress reaction in bacteria and plant chloroplasts, is a molecular switch that provides operational stress-induced reprogramming of transcription under conditions of abiotic and biotic stress. Given that the infection is… read more here.

Keywords: stringent response; response bacteria; infection; plant ... See more keywords

A Stringent Analysis of Polyphosphate Dynamics in Escherichia coli

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recommendations! Published in 2019 at "Journal of Bacteriology"

DOI: 10.1128/jb.00070-19

Abstract: During stress, bacterial cells activate a conserved pathway called the stringent response that promotes survival. Polyphosphates are long chains of inorganic phosphates that modulate this response in diverse bacterial species. ABSTRACT During stress, bacterial cells… read more here.

Keywords: polyphosphate dynamics; response; stringent analysis; polyphosphate ... See more keywords

Regulation of bacterial stringent response by an evolutionarily conserved ribosomal protein L11 methylation

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recommendations! Published in 2024 at "mBio"

DOI: 10.1128/mbio.01773-24

Abstract: ABSTRACT Lysine and arginine methylation is an important regulator of enzyme activity and transcription in eukaryotes. However, little is known about this covalent modification in bacteria. In this work, we investigated the role of methylation… read more here.

Keywords: protein; stringent response; methylation; role ... See more keywords

Understanding the Stringent Response: Experimental Context Matters

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recommendations! Published in 2023 at "mBio"

DOI: 10.1128/mbio.03404-22

Abstract: As rapidly growing bacteria begin to exhaust essential nutrients, they enter a state of reduced growth, ultimately leading to stasis or quiescence. Investigation of the response to nutrient limitation has focused largely on the consequences… read more here.

Keywords: understanding stringent; growth; starvation; response ... See more keywords

Amino Acid Starvation-Induced Glutamine Accumulation Enhances Pneumococcal Survival

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recommendations! Published in 2023 at "mSphere"

DOI: 10.1128/msphere.00625-22

Abstract: Bacteria are known to cope with amino acid starvation by halting growth and prolonging survival via the stringent response signaling system. Previous investigations have allowed us to understand how the stringent response regulates many aspects… read more here.

Keywords: acid starvation; accumulation; starvation; amino acid ... See more keywords

Role of the Extracytoplasmic Function Sigma Factor SigE in the Stringent Response of Mycobacterium tuberculosis

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recommendations! Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.02944-22

Abstract: Mycobacterium tuberculosis can enter a dormant state enabling it to establish latent infections and to become tolerant to antibacterial drugs. Dormant bacteria’s physiology and the mechanism(s) used by bacteria to enter dormancy during infection are… read more here.

Keywords: mycobacterium tuberculosis; sigma factor; low phosphate; response ... See more keywords

Pseudomonas aeruginosa Citrate Synthase GltA Influences Antibiotic Tolerance and the Type III Secretion System through the Stringent Response

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recommendations! Published in 2023 at "Microbiology Spectrum"

DOI: 10.1128/spectrum.03239-22

Abstract: Rising antimicrobial resistance imposes a severe threat to human health. It is urgent to develop novel antimicrobial strategies by understanding bacterial regulation of virulence and antimicrobial resistance determinants. ABSTRACT Carbohydrate metabolism plays essential roles in… read more here.

Keywords: antibiotic tolerance; glta; virulence; tolerance ... See more keywords

The stringent response regulator (p) ppGpp mediates virulence gene expression and survival in Erwinia amylovora

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recommendations! Published in 2020 at "BMC Genomics"

DOI: 10.1186/s12864-020-6699-5

Abstract: The nucleotide second messengers, i.e., guanosine tetraphosphate and pentaphosphate [collectively referred to as (p) ppGpp], trigger the stringent response under nutrient starvation conditions and play an essential role in virulence in the fire blight pathogen… read more here.

Keywords: ppgpp0 mutant; erwinia amylovora; response; stringent response ... See more keywords

The stringent response regulates the poly-β-hydroxybutyrate (PHB) synthesis in Azotobacter vinelandii

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recommendations! Published in 2024 at "PLOS ONE"

DOI: 10.1371/journal.pone.0299640

Abstract: The stringent response exerted by (p)ppGpp and RNA-polymerase binding protein DksA regulates gene expression in diverse bacterial species. To control gene expression (p)ppGpp, synthesized by enzymes RelA and SpoT, interacts with two sites within the… read more here.

Keywords: azotobacter vinelandii; dksa; stringent response; synthesis ... See more keywords