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   Articles with "stroke prone" as a keyword



N‐methyl‐d‐aspartate receptor dysfunction in the prefrontal cortex of stroke‐prone spontaneously hypertensive rat/Ezo as a rat model of attention deficit/hyperactivity disorder

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recommendations! Published in 2018 at "Neuropsychopharmacology Reports"

DOI: 10.1002/npr2.12007

Abstract: We previously reported that stroke‐prone spontaneously hypertensive rat/Ezo (SHRSP/Ezo) has high validity as an attention deficit/hyperactivity disorder (AD/HD) animal model, based on its behavioral phenotypes, such as inattention, hyperactivity, and impulsivity. Fronto‐cortical dysfunction is implicated… read more here.

Keywords: stroke prone; spontaneously hypertensive; hyperactivity; hypertensive rat ... See more keywords

Early and late gut microbiota signatures of stroke in high salt-fed stroke-prone spontaneously hypertensive rats

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recommendations! Published in 2024 at "Scientific Reports"

DOI: 10.1038/s41598-024-69961-9

Abstract: The high salt-fed stroke-prone spontaneously hypertensive rat (SHRSP) is a suitable tool to study the mechanisms underlying stroke pathogenesis. Salt intake modifies the gut microbiota (GM) in rats and humans and alterations of the GM… read more here.

Keywords: shrsps; stroke prone; salt; fed stroke ... See more keywords

A preventive injection of endothelial progenitor cells prolongs lifespan in stroke-prone spontaneously hypertensive rats.

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recommendations! Published in 2018 at "Clinical science"

DOI: 10.1042/cs20180360

Abstract: There is a pressing need for new approaches to prevent stroke. Endothelial progenitor cells (EPCs) promote vascular repair and revascularization in the ischemic brain. The present study sought to evaluate whether preventive delivery of EPCs… read more here.

Keywords: progenitor cells; stroke prone; preventive injection; endothelial progenitor ... See more keywords

Evaluation of Pathological Association between Stroke-Related QTL and Salt-Induced Renal Injury in Stroke-Prone Spontaneously Hypertensive Rat

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recommendations! Published in 2019 at "BioMed Research International"

DOI: 10.1155/2019/5049746

Abstract: The stroke-prone spontaneously hypertensive rat (SHRSP) suffers from severe hypertension and hypertensive organ damage such as cerebral stroke and kidney injury under salt-loading. By a quantitative trait locus (QTL) analysis between SHRSP and SHR (the… read more here.

Keywords: stroke prone; spontaneously hypertensive; salt; renal injury ... See more keywords

Gut-Microbiota Dysbiosis in Stroke-Prone Spontaneously Hypertensive Rats with Diet-Induced Steatohepatitis

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recommendations! Published in 2023 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms24054603

Abstract: Metabolic-dysfunction-associated fatty-liver disease (MAFLD) is the principal worldwide cause of liver disease. Individuals with nonalcoholic steatohepatitis (NASH) have a higher prevalence of small-intestinal bacterial overgrowth (SIBO). We examined gut-microbiota isolated from 12-week-old stroke-prone spontaneously hypertensive-5… read more here.

Keywords: gut microbiota; stroke prone; shrsp5 rats; prone spontaneously ... See more keywords

Urinary Proteome Characterization of Stroke-Prone Spontaneously Hypertensive Rats

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recommendations! Published in 2024 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms26010021

Abstract: Background Hypertension is a multifactorial, complex disease related to genetic and environmental factors and has become the most serious public health problem. This study aimed to explore the changes of hypertension based on urinary proteome.… read more here.

Keywords: hypertensive rats; spontaneously hypertensive; urinary proteome; stroke prone ... See more keywords

Favorable Effects of Virgin Coconut Oil on Neuronal Damage and Mortality after a Stroke Incidence in the Stroke-Prone Spontaneously Hypertensive Rat

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recommendations! Published in 2022 at "Life"

DOI: 10.3390/life12111857

Abstract: Stroke is consistently one of the top ten causes of morbidity and mortality globally, whose outcomes are quite variable, necessitating case-specific management. Prophylactic diets before the onset of stroke have been implicated to work. In… read more here.

Keywords: virgin coconut; coconut oil; stroke prone; group ... See more keywords