High stroma‐derived WNT5A is an indicator for low‐risk prostate cancer
Sign Up to like & getrecommendations! Published in 2021 at "FEBS Open Bio"
DOI: 10.1002/2211-5463.13131
Abstract: Prostate cancer (PCa) is a major cause of cancer‐related death in men. Tumor‐derived protein derived from Wnt5A gene (WNT5A) plays an important role in primary and metastatic PCa. Surrounding stroma cells also produce WNT5A, which… read more here.
Keywords: risk; stroma derived; high risk; derived wnt5a ... See more keywords
Stroma‐derived extracellular vesicle mRNA signatures inform histological nature of prostate cancer
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DOI: 10.1002/jev2.12150
Abstract: Abstract Histological assessment of prostate cancer is the key diagnostic test and can predict disease outcome. This is however an invasive procedure that carries associated risks, hence non‐invasive assays to support the diagnostic pathway are… read more here.
Keywords: prostate; stroma derived; prostate cancer; disease ... See more keywords
Stroma-derived HGF drives metabolic adaptation of colorectal cancer to angiogenesis inhibitors
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DOI: 10.18632/oncotarget.16942
Abstract: The role of paracrine Hepatocyte Growth Factor (HGF) in the resistance to angiogenesis inhibitors (AIs) is hidden in xenograft models because mouse HGF fails to fully activate human MET. To uncover it, we compared the… read more here.
Keywords: colorectal; angiogenesis inhibitors; stroma derived; colorectal cancer ... See more keywords
Functional Properties of Cancer Epithelium and Stroma-Derived Exosomes in Head and Neck Squamous Cell Carcinoma
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DOI: 10.3390/life12050757
Abstract: Stroma–cancer cell crosstalk involves a complex signaling network that contributes to tumor progression, including carcinogenesis, angiogenesis, migration, invasion, and therapy resistance in cancers. Exosomes, as extracellular membranous nanovesicles released by almost all types of cells,… read more here.
Keywords: cell; head neck; derived exosomes; tumor ... See more keywords