Immunosuppressive βig-h3 links tumour stroma and dysfunctional T cells in pancreatic cancer
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DOI: 10.1136/gutjnl-2018-317735
Abstract: Recent FDA approval of anti-PD-1 antibody pembrolizumab as a site-agnostic therapy for mismatch repair (MMR)–deficient solid tumours has highlighted the importance of CD8+ T cell responses and the potential of immunotherapy, even in tumour entities that are… read more here.
Keywords: immunosuppressive links; stroma dysfunctional; dysfunctional cells; tumour stroma ... See more keywords