Articles with "stromal cell" as a keyword



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Treatment and survival of patients with malignant ovarian sex cord-stromal cell tumours: An analysis of the Arbeitsgemeinschaft für Gynäkologische Onkologie (AGO) study group CORSETT database.

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Published in 2023 at "Journal of surgical oncology"

DOI: 10.1002/jso.27248

Abstract: BACKGROUND Malignant sex cord-stromal cell tumours (SCST) account for only 7% of ovarian malignancies. The Arbeitsgemeinschaft fuer Gynaekologische Onkologie (AGO) study group has established a clinicopathological database to provide an overview of the current treatment… read more here.

Keywords: cell; analysis; stromal cell; sex cord ... See more keywords
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Stromal cell derived factor 1 plasmid to regenerate the anal sphincters

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Published in 2022 at "Journal of Tissue Engineering and Regenerative Medicine"

DOI: 10.1002/term.3283

Abstract: The aim of this study was to evaluate regeneration of a chronic large anal sphincter defect in a pig model after treatment with a plasmid encoding Stromal Cell Derived Factor‐1(SDF‐1). read more here.

Keywords: factor plasmid; derived factor; stromal cell; cell derived ... See more keywords
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Novel Models to Study Stromal Cell-Leukocyte Interactions in Health and Disease.

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Published in 2018 at "Advances in experimental medicine and biology"

DOI: 10.1007/978-3-319-78127-3_8

Abstract: To study human immunology in general and stromal immunology in particular, it is highly motivated to move from monolayers to 3D cultures, such as organotypic models, that better mimic the function of living tissue. These… read more here.

Keywords: stromal cell; health disease; disease; immunology ... See more keywords
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Megakaryocyte-stromal cell interactions: effect on megakaryocyte proliferation, proplatelet production, and survival.

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Published in 2022 at "Experimental hematology"

DOI: 10.1016/j.exphem.2022.01.002

Abstract: Bone marrow stromal cells provide a proper environment for the development of hematologic lineages. The incorporation of different stromal cells to in vitro culture systems would be an attractive model to study megakaryopoiesis and thrombopoiesis. Our… read more here.

Keywords: survival; megakaryocyte; stromal cell; mks ... See more keywords
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Umbilical cord-derived mesenchymal stromal cell-conditioned medium exerts in vitro antiaging effects in human fibroblasts.

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Published in 2017 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2016.12.001

Abstract: BACKGROUND AIMS Chronic wounds are a common complication of diabetes. Fibroblast-myofibroblast differentiation is important for wound repair, which is commonly impaired in non-healing wounds, and the underlying mechanisms need to be further elucidated. METHODS We… read more here.

Keywords: stromal cell; conditioned medium; mesenchymal stromal; cell conditioned ... See more keywords
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Immune regulatory targets of mesenchymal stromal cell exosomes/small extracellular vesicles in tissue regeneration.

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Published in 2018 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2018.09.008

Abstract: Mesenchymal stromal cell (MSC) therapies have demonstrated therapeutic efficacy in a wide-ranging array of tissue injury and disease indications. An important aspect of MSC-mediated therapeutic activities is immune modulation. Consistent with the concentration of MSC… read more here.

Keywords: mesenchymal stromal; stromal cell; regeneration; tissue ... See more keywords
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Is mesenchymal stromal cell apoptosis necessary for their immunomodulatory capacity?

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Published in 2020 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2020.03.145

Abstract: Background & Aim Mesenchymal stromal cells (MSCs) exhibit therapeutic potential in a broad range of disease conditions. However, the lack of clarity around their mechanism of action presents a significant hurdle in their clinical utility.… read more here.

Keywords: mesenchymal stromal; apoptosis; stromal cell; msc ... See more keywords
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Mesenchymal stromal cell variables influencing clinical potency: the impact of viability, fitness, route of administration and host predisposition.

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Published in 2021 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2020.11.007

Abstract: The International Society for Cell & Gene Therapy mesenchymal stromal cell (MSC) committee has been an interested observer of community interests in all matters related to MSC identity, mechanism of action, potency assessment and etymology,… read more here.

Keywords: mesenchymal stromal; potency; stromal cell; impact ... See more keywords
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Mesenchymal stromal cell therapy for coronavirus disease 2019: which? when? and how much?

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Published in 2021 at "Cytotherapy"

DOI: 10.1016/j.jcyt.2021.04.004

Abstract: Mesenchymal Stromal Cells (MSCs) are under active consideration as a treatment strategy to control the hyperinflammation and slow disease progression in COVID-19. The possible mechanism of protection through their immunoregulatory and paracrine action has been… read more here.

Keywords: stromal cell; cell therapy; mesenchymal stromal; disease ... See more keywords
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Marijuana-derived cannabinoids inhibit uterine endometrial stromal cell decidualization and compromise trophoblast-endometrium cross-talk.

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Published in 2019 at "Reproductive toxicology"

DOI: 10.1016/j.reprotox.2019.05.064

Abstract: Marijuana (cannabis) use by pregnant women in the United States is increasing and there is a dire need to understand the beneficial or harmful effects of cannabis during pregnancy. Uterine endometrial stromal cells are fibroblast-like… read more here.

Keywords: cell decidualization; uterine endometrial; stromal cell; endometrial stromal ... See more keywords
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Defining the optimal historical control group for a phase 1 trial of mesenchymal stromal cell delivery through cardiopulmonary bypass in neonates and infants.

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Published in 2022 at "Cardiology in the young"

DOI: 10.1017/s1047951122002633

Abstract: OBJECTIVE The Mesenchymal Stromal Cell Delivery through Cardiopulmonary Bypass in Pediatric Cardiac Surgery study is a prospective, open-label, single-centre, dose-escalation phase 1 trial assessing the safety/feasibility of delivering mesenchymal stromal cells to neonates/infants during cardiac… read more here.

Keywords: mesenchymal stromal; cardiopulmonary bypass; group; stromal cell ... See more keywords