A Novel Synthetic, Xeno‐Free Biomimetic Surface for Serum‐Free Expansion of Human Mesenchymal Stromal Cells
Sign Up to like & getrecommendations! Published in 2020 at "Advanced Biosystems"
DOI: 10.1002/adbi.202000008
Abstract: Human mesenchymal stromal cells (hMSCs) have enormous potential for the treatment of various inflammatory and degenerative diseases. Their manufacturing for cell‐based therapies requires extensive ex vivo expansion and optimal growth conditions. To support cell adhesion,… read more here.
Keywords: human mesenchymal; mesenchymal stromal; expansion; stromal cells ... See more keywords
Controlled Apoptosis of Stromal Cells to Engineer Human Microlivers.
Sign Up to like & getrecommendations! Published in 2020 at "Advanced functional materials"
DOI: 10.1002/adfm.201910442
Abstract: Engineered tissue models comprise a variety of multiplexed ensembles in which combinations of epithelial, stromal, and immune cells give rise to physiologic function. Engineering spatiotemporal control of cell-cell and cell-matrix interactions within these 3D multicellular… read more here.
Keywords: apoptosis stromal; apoptosis; stromal cells; cells engineer ... See more keywords
Acute Myeloid Leukemia Cells Educate Mesenchymal Stromal Cells toward an Adipogenic Differentiation Propensity with Leukemia Promotion Capabilities
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DOI: 10.1002/advs.202105811
Abstract: Mesenchymal stromal cells (MSCs) are essential elements of the bone marrow (BM) microenvironment, which have been widely implicated in pathways that contribute to leukemia growth and resistance. Recent reports showed genotypic and phenotypic alterations in… read more here.
Keywords: myeloid leukemia; mesenchymal stromal; leukemia; acute myeloid ... See more keywords
Dimethyloxalylglycine, a small molecule, synergistically increases the homing and angiogenic properties of human mesenchymal stromal cells when cultured as 3D spheroids
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202000389
Abstract: Strategies aiming at increasing the survival and paracrine activity of human mesenchymal stromal cells (MSCs) are of utmost importance to achieve the full therapeutic potential of these cells. Herein, we propose both physical and biochemical… read more here.
Keywords: human mesenchymal; mesenchymal stromal; cells cultured; small molecule ... See more keywords
Umbilical cord derived mesenchymal stromal cells in microcarrier based industrial scale culture sustain the immune regulatory functions
Sign Up to like & getrecommendations! Published in 2021 at "Biotechnology Journal"
DOI: 10.1002/biot.202000558
Abstract: Mesenchymal stromal cells (MSCs) have been isolated from numerous sources and are potentially therapeutic against various diseases. Umbilical cord‐derived MSCs (UC‐MSCs) are considered superior to other tissue‐derived MSCs since they have a higher proliferation rate… read more here.
Keywords: mesenchymal stromal; stromal cells; microcarrier based; mscs ... See more keywords
Human adipose mesenchymal stromal cells growing into PCL‐nHA electrospun scaffolds undergo hypoxia adaptive ultrastructural changes
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology Journal"
DOI: 10.1002/biot.202200413
Abstract: Human Adipose‐Derived Mesenchymal Stem/Stromal Cells (hAD‐MSCs) have great potential for tissue regeneration. Since transplanted hAD‐MSCs are likely to be placed in a hypoxic environment, culturing the cells under hypoxic conditions might improve their post‐transplantation survival… read more here.
Keywords: hypoxic environment; nha nanofibers; human adipose; pcl nha ... See more keywords
PRESERVATION OF CRITICAL QUALITY ATTRIBUTES OF MESENCHYMAL STROMAL CELLS IN 3D BIOPRINTED STRUCTURES BY USING NATURAL HYDROGEL SCAFFOLDS.
Sign Up to like & getrecommendations! Published in 2023 at "Biotechnology and bioengineering"
DOI: 10.1002/bit.28381
Abstract: 3D bioprinting is an emerging technology that enables complex spatial modelling of cell-based tissue engineering products, whose therapeutic potential in regenerative medicine is enormous. However, its success largely depends on the definition of a bioprintable… read more here.
Keywords: quality attributes; mesenchymal stromal; using natural; natural hydrogel ... See more keywords
Expansion of adipose tissue‐derived stromal cells at “physiologic” hypoxia attenuates replicative senescence
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DOI: 10.1002/cbf.3267
Abstract: Multipotent mesenchymal stromal cells are considered as a perspective tool in cell therapy and regenerative medicine. Unfortunately, autologous cell therapy does not always provide positive outcomes in elder donors, perhaps as a result of the… read more here.
Keywords: replicative senescence; stromal cells; senescence; adipose tissue ... See more keywords
Anti‐apoptotic effects of adipose‐derived adherent stromal cells in mesenchymal stem cells exposed to oxidative stress
Sign Up to like & getrecommendations! Published in 2018 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3338
Abstract: Adipose‐derived stromal vascular fractions (SVFs) are a heterogeneous collection of cells, and their regenerative modality has been applied in various animal experiments and clinical trials. Despite the attractive advantages of SVFs in clinical interventions, the… read more here.
Keywords: heart; stromal cells; mesenchymal stem; adipose derived ... See more keywords
S100A7 promotes the development of human endometriosis by activating NF‐κB signaling pathway in endometrial stromal cells
Sign Up to like & getrecommendations! Published in 2021 at "Cell Biology International"
DOI: 10.1002/cbin.11578
Abstract: Endometriosis (EM) is a chronic inflammatory disease affecting women aged between 23 and 42 years with a prevalence of 6%–10%. S100A7, a member of the S100 protein family, has been implicated in promoting inflammation. However, the… read more here.
Keywords: endometriosis; stromal cells; endometrial stromal; expression ... See more keywords
LncRNA MALAT1 promotes decidualization of endometrial stromal cells via sponging miR‐498‐3p and targeting histone deacetylase 4
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biology International"
DOI: 10.1002/cbin.11814
Abstract: Decidualization of human endometrial stromal cells (hESCs) is important for the maintenance of a successful pregnancy. Histone deacetylase 4 (HDAC4) was reported to be involved in the dysfunction of decidua‐derived mesenchymal stem cells. However, the… read more here.
Keywords: mir 498; endometrial stromal; hescs; hdac4 ... See more keywords