Long-term exposure to carcinoma-associated fibroblasts makes breast cancer cells addictive to integrin β1
Sign Up to like & getrecommendations! Published in 2018 at "Oncotarget"
DOI: 10.18632/oncotarget.25183
Abstract: We studied the long-term effect of stromal factors on the development of fulvestrant-resistance (FR) and fulvestrant-induced dormancy (D). Sublines established from stroma-treated FR-cells (C-FR cells) and D-cells (C-D cells) show permanently high expression of integrin… read more here.
Keywords: long term; stromal factors; breast cancer;
Fascin is involved in cancer cell invasion and is regulated by stromal factors.
Sign Up to like & getrecommendations! Published in 2019 at "Oncology reports"
DOI: 10.3892/or.2018.6847
Abstract: The tumor microenvironment plays an important role in cancer growth, invasion and metastasis. The stroma surrounding a tumor is known to contain a variety of factors that can increase angiogenesis, cancer growth and tumor progression.… read more here.
Keywords: invasion; involved cancer; stromal factors; expression ... See more keywords