ESTIMATE algorithm is not appropriate for inferring tumor purity and stromal and immune cell admixture in hematopoietic or stromal tumors
Sign Up to like & getrecommendations! Published in 2020 at "Cancer Immunology, Immunotherapy"
DOI: 10.1007/s00262-020-02526-7
Abstract: With great interest, we have read the recent article entitled “Identification of prognostic genes in the acute myeloid leukemia immune microenvironment based on TCGA data analysis” [1] (by Yan et al. Cancer Immunol Immunother (2019)… read more here.
Keywords: estimate algorithm; estimate; stromal immune; cancer ... See more keywords
Stromal–immune cell crosstalk deciphered in Dupuytren disease
Sign Up to like & getrecommendations! Published in 2019 at "Nature Reviews Rheumatology"
DOI: 10.1038/s41584-019-0363-y
Abstract: Fibrotic diseases are some of the most challenging conditions to treat owing to a lack of effective therapies. Drug development for such conditions is hampered by a lack of suitable animal models and a poor… read more here.
Keywords: immune cell; dupuytren disease; stromal immune; study ... See more keywords
Comprehensive Analyses of Stromal-Immune Score-Related Competing Endogenous RNA Networks In Colon Adenocarcinoma
Sign Up to like & getrecommendations! Published in 2022 at "Disease Markers"
DOI: 10.1155/2022/4235305
Abstract: Although recent clinical investigations emphasize the roles of myriad diversities of RNAs in stromal and immune components in the tumor microenvironment, especially in colon adenocarcinoma, however, analyses of “competing endogenous RNAs (ceRNA)” network in association… read more here.
Keywords: immune score; colon adenocarcinoma; stromal immune; cerna network ... See more keywords
Abstract 3140: Computational modeling of stromal-immune cell interactions in triple-negative breast cancer
Sign Up to like & getrecommendations! Published in 2023 at "Cancer Research"
DOI: 10.1158/1538-7445.am2023-3140
Abstract: Breast cancer is the most common cancer type in women worldwide, and it represents the second most common cause of cancer deaths. Compared with other breast cancer subtypes, triple-negative breast cancer (TNBC) has the worst… read more here.
Keywords: cell; immune cell; stromal immune; breast cancer ... See more keywords
Development of primary human pancreatic cancer organoids, matched stromal and immune cells and 3D tumor microenvironment models
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DOI: 10.1186/s12885-018-4238-4
Abstract: BackgroundPatient-derived tumor models are the new standard for pre-clinical drug testing and biomarker discovery. However, the emerging technology of primary pancreatic cancer organoids has not yet been broadly implemented in research, and complex organotypic models… read more here.
Keywords: stromal immune; pancreatic cancer; cancer organoids; cancer ... See more keywords
Prognostic stromal and immune response expression patterns in early-stage colorectal cancer predicted by genes intrinsically expressed by tumor epithelial cells.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Clinical Oncology"
DOI: 10.1200/jco.2019.37.15_suppl.3601
Abstract: 3601 Background: High stromal content (CMS4) and immune infiltration (CMS1) are important features of the tumor micro-environment (TME) in early stage colorectal cancer, with poor and good RFS prognosis, respectively. However, it remains unclear how… read more here.
Keywords: expression; stage colorectal; stromal immune; early stage ... See more keywords
Identification of Diagnostic Biomarkers Associated with Stromal and Immune Cell Infiltration in Fatty Infiltration After Rotator Cuff Tear by Integrating Bioinformatic Analysis and Machine-Learning
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of General Medicine"
DOI: 10.2147/ijgm.s354741
Abstract: Purpose The present study aimed to explore potential diagnostic biomarkers for fatty infiltration (FI) of the rotator cuff muscles after rotator cuff tear (RCT) and investigate the influence of stromal and immune cell infiltration on… read more here.
Keywords: infiltration; cell; cell infiltration; immune cell ... See more keywords
Spheroid Formation and Peritoneal Metastasis in Ovarian Cancer: The Role of Stromal and Immune Components
Sign Up to like & getrecommendations! Published in 2022 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms23116215
Abstract: Ovarian cancer (OC) is one of the most common gynecological cancers, with the worst prognosis and the highest mortality rate. Peritoneal dissemination (or carcinomatosis) accompanied by ascites formation is the most unfavorable factor in the… read more here.
Keywords: spheroid formation; stromal immune; ovarian cancer; immune components ... See more keywords