Articles with "stromal stem" as a keyword



Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels.

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Published in 2017 at "Acta biomaterialia"

DOI: 10.1016/j.actbio.2017.01.021

Abstract: Mesenchymal stromal/stem cells (MSCs) have demonstrated pro-healing properties including an anti-inflammatory cytokine profile and the promotion of angiogenesis via expression of growth factors in pre-clinical models. MSCs encapsulated in poly(ethylene glycol) diacrylate (PEGdA) and thiolated… read more here.

Keywords: minocycline; stromal stem; wound healing; mesenchymal stromal ... See more keywords

In Vivo Fate of CXCR2-Overexpressing Mesenchymal Stromal/Stem Cells in Pulmonary Diseases Monitored by Near-Infrared Region 2 Imaging.

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Published in 2023 at "ACS applied materials & interfaces"

DOI: 10.1021/acsami.3c01741

Abstract: Lung-associated diseases pose a huge threat to human society. Mesenchymal stromal/stem cells (MSCs) hold great promise in the treatment of pulmonary diseases through cell transdifferentiation, paracrine factors, immune regulation, EV secretion, and drug loading. However,… read more here.

Keywords: mesenchymal stromal; infrared region; pulmonary diseases; near infrared ... See more keywords

Enhancing Optical Coherence Tomography Contrast of Corneal Stromal Stem Cells Using Gold Nanobipyramids

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Published in 2025 at "ACS Applied Nano Materials"

DOI: 10.1021/acsanm.5c04264

Abstract: Gold nanobipyramids (GNBPs) were investigated as near-infrared contrast agents for optical coherence tomography (OCT) tracking of human corneal stromal stem cells (CSSCs). GNBPs with various longitudinal localized surface plasmon resonance peaks were synthesized, and the… read more here.

Keywords: gold nanobipyramids; contrast; stromal stem; corneal ... See more keywords

Relevance of RNA to the therapeutic efficacy of mesenchymal stromal/stem cells extracellular vesicles

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Published in 2024 at "RNA Biology"

DOI: 10.1080/15476286.2024.2446868

Abstract: ABSTRACT Mesenchymal Stromal/Stem Cells (MSCs) are among the most frequently studied cell types in clinical trials, and their small extracellular vesicles (sEVs) are now being extensively investigated for therapeutic applications. The RNA cargo of MSC-sEVs,… read more here.

Keywords: extracellular vesicles; rna; mesenchymal stromal; stromal stem ... See more keywords

Adipose-derived Stromal/Stem Cell Response to Tumors and Wounds: Evaluation of Patient Age.

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Published in 2022 at "Stem cells and development"

DOI: 10.1089/scd.2021.0280

Abstract: Tumors were characterized as non-healing wounds by Virchow in 1858 and Dvorak in 1986. Since then, researchers have analyzed tumors from a new perspective. The parallels between tumorigenesis and physiological wound healing can provide a… read more here.

Keywords: wound healing; age; tumors wounds; stromal stem ... See more keywords

Alteration of transcriptomic profile and anti-septic efficacy of adipose-derived mesenchymal stromal/stem cells under different culture conditions.

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Published in 2022 at "Stem cells and development"

DOI: 10.1089/scd.2022.0238

Abstract: Mesenchymal stromal/stem cells (MSCs) are a promising therapeutic agent for various diseases, including sepsis. However, translating MSC therapy to clinical applications remains challenging due to variations in the properties of MSCs under different preparation conditions.… read more here.

Keywords: mesenchymal stromal; adscs; hpl adscs; stromal stem ... See more keywords

Immunomodulatory Functions of Adipose Mesenchymal Stromal/Stem Cell Derived From Donors With Type 2 Diabetes and Obesity on CD4 T Cells

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Published in 2023 at "Stem Cells"

DOI: 10.1093/stmcls/sxad021

Abstract: Abstract For adipose stromal/stem cell (ASCs)-based immunomodulatory therapies, it is important to study how donor characteristics, such as obesity and type 2 diabetes (T2D), influence ASCs efficacy. Here, ASCs were obtained from 2 groups, donors… read more here.

Keywords: cell; cd4 cells; cd4; expression ... See more keywords

Similarities between Tumour Immune Response and Chronic Wound Microenvironment: Influence of Mesenchymal Stromal/Stem Cells

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Published in 2021 at "Journal of Immunology Research"

DOI: 10.1155/2021/6649314

Abstract: Tumours are characterized by a state of chronic inflammation and are regarded as wounds that never heal. Mesenchymal stromal/stem cells (MSCs) are being considered as a possible treatment option. While MSCs can regulate the immune… read more here.

Keywords: stromal stem; mesenchymal stromal; role; mscs ... See more keywords

Effects of Bariatric Surgery-Related Weight Loss on the Characteristics, Metabolism, and Immunomodulation of Adipose Stromal/Stem Cells in a Follow-Up Study

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Published in 2025 at "Stem Cells International"

DOI: 10.1155/sci/1212255

Abstract: Background: The success of adipose stromal/stem cell (ASC)-based therapies may depend on donor characteristics such as body mass index (BMI). A high BMI may negatively impact the therapeutic potential of ASCs, but the effects of… read more here.

Keywords: loss; adipose stromal; weight loss; stromal stem ... See more keywords

Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation

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Published in 2022 at "Cell Transplantation"

DOI: 10.1177/09636897221089629

Abstract: Mesenchymal stromal/stem cells (MSCs) have shown potential in the treatment of degenerative diseases, including ischemia/reperfusion injury (IRI), which occurs during organ transplantation and represents the main cause of post-transplant graft dysfunction. However, MSCs have heterogeneous… read more here.

Keywords: mesenchymal stromal; iri; adipose derived; stromal stem ... See more keywords

Systematic review and meta-analysis of mesenchymal stromal/stem cells as strategical means for the treatment of COVID-19

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Published in 2023 at "Therapeutic Advances in Respiratory Disease"

DOI: 10.1177/17534666231158276

Abstract: Background: In coronavirus disease 2019 (COVID-19) patients, elevated levels of inflammatory cytokines from over stimulation of immune cells have become a concern due to the potential outburst of cytokine storm that damages the tissues and… read more here.

Keywords: meta analysis; mesenchymal stromal; covid; stromal stem ... See more keywords