Minocycline enhances the mesenchymal stromal/stem cell pro-healing phenotype in triple antimicrobial-loaded hydrogels.
Sign Up to like & getrecommendations! Published in 2017 at "Acta biomaterialia"
DOI: 10.1016/j.actbio.2017.01.021
Abstract: Mesenchymal stromal/stem cells (MSCs) have demonstrated pro-healing properties including an anti-inflammatory cytokine profile and the promotion of angiogenesis via expression of growth factors in pre-clinical models. MSCs encapsulated in poly(ethylene glycol) diacrylate (PEGdA) and thiolated… read more here.
Keywords: minocycline; stromal stem; wound healing; mesenchymal stromal ... See more keywords
In Vivo Fate of CXCR2-Overexpressing Mesenchymal Stromal/Stem Cells in Pulmonary Diseases Monitored by Near-Infrared Region 2 Imaging.
Sign Up to like & getrecommendations! Published in 2023 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.3c01741
Abstract: Lung-associated diseases pose a huge threat to human society. Mesenchymal stromal/stem cells (MSCs) hold great promise in the treatment of pulmonary diseases through cell transdifferentiation, paracrine factors, immune regulation, EV secretion, and drug loading. However,… read more here.
Keywords: mesenchymal stromal; infrared region; pulmonary diseases; near infrared ... See more keywords
Adipose-derived Stromal/Stem Cell Response to Tumors and Wounds: Evaluation of Patient Age.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2021.0280
Abstract: Tumors were characterized as non-healing wounds by Virchow in 1858 and Dvorak in 1986. Since then, researchers have analyzed tumors from a new perspective. The parallels between tumorigenesis and physiological wound healing can provide a… read more here.
Keywords: wound healing; age; tumors wounds; stromal stem ... See more keywords
Alteration of transcriptomic profile and anti-septic efficacy of adipose-derived mesenchymal stromal/stem cells under different culture conditions.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2022.0238
Abstract: Mesenchymal stromal/stem cells (MSCs) are a promising therapeutic agent for various diseases, including sepsis. However, translating MSC therapy to clinical applications remains challenging due to variations in the properties of MSCs under different preparation conditions.… read more here.
Keywords: mesenchymal stromal; adscs; hpl adscs; stromal stem ... See more keywords
Immunomodulatory Functions of Adipose Mesenchymal Stromal/Stem Cell Derived From Donors With Type 2 Diabetes and Obesity on CD4 T Cells
Sign Up to like & getrecommendations! Published in 2023 at "Stem Cells"
DOI: 10.1093/stmcls/sxad021
Abstract: Abstract For adipose stromal/stem cell (ASCs)-based immunomodulatory therapies, it is important to study how donor characteristics, such as obesity and type 2 diabetes (T2D), influence ASCs efficacy. Here, ASCs were obtained from 2 groups, donors… read more here.
Keywords: cell; cd4 cells; cd4; expression ... See more keywords
Similarities between Tumour Immune Response and Chronic Wound Microenvironment: Influence of Mesenchymal Stromal/Stem Cells
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Immunology Research"
DOI: 10.1155/2021/6649314
Abstract: Tumours are characterized by a state of chronic inflammation and are regarded as wounds that never heal. Mesenchymal stromal/stem cells (MSCs) are being considered as a possible treatment option. While MSCs can regulate the immune… read more here.
Keywords: stromal stem; mesenchymal stromal; role; mscs ... See more keywords
Adipose-Derived Mesenchymal Stromal/Stem Cell Line Prevents Hepatic Ischemia/Reperfusion Injury in Rats by Inhibiting Inflammasome Activation
Sign Up to like & getrecommendations! Published in 2022 at "Cell Transplantation"
DOI: 10.1177/09636897221089629
Abstract: Mesenchymal stromal/stem cells (MSCs) have shown potential in the treatment of degenerative diseases, including ischemia/reperfusion injury (IRI), which occurs during organ transplantation and represents the main cause of post-transplant graft dysfunction. However, MSCs have heterogeneous… read more here.
Keywords: mesenchymal stromal; iri; adipose derived; stromal stem ... See more keywords
Systematic review and meta-analysis of mesenchymal stromal/stem cells as strategical means for the treatment of COVID-19
Sign Up to like & getrecommendations! Published in 2023 at "Therapeutic Advances in Respiratory Disease"
DOI: 10.1177/17534666231158276
Abstract: Background: In coronavirus disease 2019 (COVID-19) patients, elevated levels of inflammatory cytokines from over stimulation of immune cells have become a concern due to the potential outburst of cytokine storm that damages the tissues and… read more here.
Keywords: meta analysis; mesenchymal stromal; covid; stromal stem ... See more keywords
Altered pathways of keratinization, extracellular matrix generation, angiogenesis, and stromal stem cells proliferation in patients with systemic sclerosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Scleroderma and Related Disorders"
DOI: 10.1177/23971983221130145
Abstract: Objective: Systemic sclerosis is characterized by endothelial dysfunction, autoimmunity abnormalities, and fibrosis of the skin and internal organs. The pathogenetic mechanisms underlying systemic sclerosis vasculopathy are still not clarified. A complex cellular and extracellular network… read more here.
Keywords: extracellular matrix; systemic sclerosis; sclerosis; stromal stem ... See more keywords
3D Functional Corneal Stromal Tissue Equivalent Based on Corneal Stromal Stem Cells and Multi-Layered Silk Film Architecture
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0169504
Abstract: The worldwide need for human cornea equivalents continues to grow. Few clinical options are limited to allogenic and synthetic material replacements. We hypothesized that tissue engineered human cornea systems based on mechanically robust, patterned, porous,… read more here.
Keywords: stromal stem; corneal; tissue; corneal stromal ... See more keywords
Dynamic Culture of Mesenchymal Stromal/Stem Cell Spheroids and Secretion of Paracrine Factors
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2022.916229
Abstract: In recent years, conditioned medium (CM) obtained from the culture of mesenchymal stromal/stem cells (MSCs) has been shown to effectively promote tissue repair and modulate the immune response in vitro and in different animal models,… read more here.
Keywords: culture; mesenchymal stromal; dynamic culture; stromal stem ... See more keywords