Articles with "stromal tumours" as a keyword



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Gastrointestinal Stromal Tumours (GIST): A Review of Cases from Nigeria

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Published in 2019 at "Journal of Gastrointestinal Cancer"

DOI: 10.1007/s12029-019-00318-6

Abstract: Gastrointestinal stromal tumours (GIST) are rare and studies on GIST in Nigeria are extremely uncommon. This study aims to achieve a comprehensive systematic review of the cases of this tumour in Nigerians. A systematic search… read more here.

Keywords: tumours gist; gastrointestinal stromal; review cases; stromal tumours ... See more keywords
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Evaluation of molecular analysis in challenging ovarian sex cord-stromal tumours: a review of 50 cases.

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Published in 2020 at "Pathology"

DOI: 10.1016/j.pathol.2020.06.008

Abstract: Molecular profiling was performed in 50 problematic ovarian sex cord-stromal tumours (SCSTs) most of which were seen in consultation. Following analysis, 17 were classified as adult granulosa cell tumour (AGCT), 16 of which showed a… read more here.

Keywords: ovarian sex; cord stromal; analysis; sex cord ... See more keywords
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Clinical outcomes of surgical and imatinib treatment for rectal gastrointestinal stromal tumours: retrospective cohort study

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Published in 2022 at "BJS Open"

DOI: 10.1093/bjsopen/zrac067

Abstract: Abstract Background Rectal gastrointestinal stromal tumours (GISTs) are rare and treated mainly by radical surgery. Although the importance of perioperative imatinib has been recognized, there are few reports on its outcomes. Method Consecutive patients diagnosed… read more here.

Keywords: imatinib; surgery; rectal gastrointestinal; stromal tumours ... See more keywords
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Is multivisceral resection in locally advanced gastrointestinal stromal tumours an acceptable strategy?

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Published in 2017 at "ANZ Journal of Surgery"

DOI: 10.1111/ans.13518

Abstract: Gastrointestinal stromal tumours (GISTs) represent the most common mesenchymal tumour of the gastrointestinal tract. Although the efficacy of targeted therapy cannot be over‐emphasized, surgery remains the only curative primary treatment for patients with localized disease.… read more here.

Keywords: advanced gastrointestinal; gastrointestinal stromal; stromal tumours; locally advanced ... See more keywords
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Optimizing the dose in patients treated with imatinib as first line treatment for gastrointestinal stromal tumours: A cost‐effectiveness study

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Published in 2019 at "British Journal of Clinical Pharmacology"

DOI: 10.1111/bcp.13990

Abstract: Patients with metastatic gastrointestinal stromal tumours (GIST) are treated in first line with the oral tyrosine kinase inhibitor, imatinib, until progressive disease. With this fixed dosing regimen, only approximately 40% of patients reach adequate plasma… read more here.

Keywords: line; first line; gastrointestinal stromal; treated imatinib ... See more keywords
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Microscopic gastrointestinal stromal tumours: a clinical and molecular study of 13 cases

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Published in 2017 at "Histopathology"

DOI: 10.1111/his.13049

Abstract: Recent literature suggests that clinically silent, microscopic gastrointestinal stromal tumours (micro‐GISTs) are common incidental findings. The aim of this study was to examine the histological, immunohistochemical and molecular characteristics of these tumours, which we have… read more here.

Keywords: clinical molecular; study; gastrointestinal stromal; microscopic gastrointestinal ... See more keywords
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Dataset for reporting of gastrointestinal stromal tumours: recommendations from the International Collaboration on Cancer Reporting (ICCR)

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Published in 2022 at "Histopathology"

DOI: 10.1111/his.14791

Abstract: Gastrointestinal stromal tumours (GISTs) are the most common mesenchymal tumours of the gastrointestinal tract and are among the most frequent sarcomas. Accurate diagnosis, classification, and reporting are critical for prognostication and patient management, including selection… read more here.

Keywords: pathology; stromal tumours; collaboration cancer; international collaboration ... See more keywords
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Myoid gonadal stromal tumours are characterised by recurrent chromosome‐level copy number gains: molecular assessment of a multi‐institutional series

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Published in 2022 at "Histopathology"

DOI: 10.1111/his.14825

Abstract: Myoid gonadal stromal tumours (MGST) represent a rare type of testicular sex cord‐stromal tumour that has recently been recognised as a distinct entity by the World Health Organization (WHO) classification of genitourinary tumours. MGSTs affect… read more here.

Keywords: chromosome; stromal tumours; copy number; level ... See more keywords
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Rectovaginal extragastrointestinal stromal tumour (EGIST): an additional entity to be considered in the differential diagnosis of tumours of the rectovaginal septum

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Published in 2021 at "BMJ Case Reports"

DOI: 10.1136/bcr-2020-237669

Abstract: Gastrointestinal stromal tumours (GISTs) are rare - and rectovaginal extragastrointestinal stromal tumours (RV-EGISTs) even rarer. We share a case of RV-EGIST, complemented by high-quality radiological and surgical images. A review of current literature pertaining to… read more here.

Keywords: extragastrointestinal stromal; rectovaginal extragastrointestinal; diagnosis; differential diagnosis ... See more keywords
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New frontiers in the medical management of gastrointestinal stromal tumours

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Published in 2019 at "Therapeutic Advances in Medical Oncology"

DOI: 10.1177/1758835919841946

Abstract: The tyrosine kinase inhibitor (TKI) imatinib has radically changed the natural history of KIT-driven gastrointestinal stromal tumours (GISTs). Approved second-line and third-line medical therapies are represented by the TKIs sunitinib and regorafenib, respectively. While imatinib… read more here.

Keywords: management gastrointestinal; new frontiers; frontiers medical; gastrointestinal stromal ... See more keywords
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Perspectives on the evolving state of the art management of gastrointestinal stromal tumours.

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Published in 2018 at "Translational gastroenterology and hepatology"

DOI: 10.21037/tgh.2018.04.02

Abstract: Gastrointestinal stromal tumours (GISTs) represent a very exciting tumour entity for the medical oncologist. There has been extensive clinical and preclinical research dissecting the natural behaviour, molecular landscape and therapeutic responsiveness of this rare mesenchymal… read more here.

Keywords: gastrointestinal stromal; art management; state art; stromal tumours ... See more keywords