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Mutation‐related magnetization‐transfer, not axon density, drives white matter differences in premanifest Huntington disease: Evidence from in vivo ultra‐strong gradient MRI

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Published in 2022 at "Human Brain Mapping"

DOI: 10.1002/hbm.25859

Abstract: White matter (WM) alterations have been observed in Huntington disease (HD) but their role in the disease‐pathophysiology remains unknown. We assessed WM changes in premanifest HD by exploiting ultra‐strong‐gradient magnetic resonance imaging (MRI). This allowed… read more here.

Keywords: ultra strong; disease; mtr; strong gradient ... See more keywords