Is the Mutation Rate Lower in Genomic Regions of Stronger Selective Constraints?
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DOI: 10.1093/molbev/msac169
Abstract: Abstract A study of the plant Arabidopsis thaliana detected lower mutation rates in genomic regions where mutations are more likely to be deleterious, challenging the principle that mutagenesis is blind to its consequence. To examine… read more here.
Keywords: selective constraints; mutation rate; regions stronger; genomic regions ... See more keywords
Stronger selective constraint on downstream genes in the oxidative phosphorylation pathway of cetaceans
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DOI: 10.1111/jeb.13213
Abstract: The oxidative phosphorylation (OXPHOS) pathway is an efficient way to produce energy via adenosine triphosphate (ATP), which is critical for sustaining an energy supply for cetaceans in a hypoxic environment. Several studies have shown that… read more here.
Keywords: pathway; selective constraint; stronger selective; downstream genes ... See more keywords