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Published in 2018 at "PLoS ONE"
DOI: 10.1371/journal.pone.0198854
Abstract: In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of missing…
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Keywords:
protein;
flexibility;
saflex structural;
structural alphabet ... See more keywords
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Published in 2020 at "Biomolecules"
DOI: 10.3390/biom10071080
Abstract: Intrinsically-disordered protein (IDP) characterization was an amazing change of paradigm in our classical sequence-structure-function theory. Moreover, IDPs are over-represented in major disease pathways and are now often targeted using small molecules for therapeutic purposes. This…
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Keywords:
protein;
analysis;
disorder;
structural alphabet ... See more keywords