Articles with "structural alphabet" as a keyword



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SAFlex: A structural alphabet extension to integrate protein structural flexibility and missing data information

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Published in 2018 at "PLoS ONE"

DOI: 10.1371/journal.pone.0198854

Abstract: In this paper, we describe SAFlex (Structural Alphabet Flexibility), an extension of an existing structural alphabet (HMM-SA), to better explore increasing protein three dimensional structure information by encoding conformations of proteins in case of missing… read more here.

Keywords: protein; flexibility; saflex structural; structural alphabet ... See more keywords
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Analysis of Protein Disorder Predictions in the Light of a Protein Structural Alphabet

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Published in 2020 at "Biomolecules"

DOI: 10.3390/biom10071080

Abstract: Intrinsically-disordered protein (IDP) characterization was an amazing change of paradigm in our classical sequence-structure-function theory. Moreover, IDPs are over-represented in major disease pathways and are now often targeted using small molecules for therapeutic purposes. This… read more here.

Keywords: protein; analysis; disorder; structural alphabet ... See more keywords