A unified model of shared brain structural alterations in patients with different mental disorders who experience own‐thought auditory verbal hallucinations—A pilot study
Sign Up to like & getrecommendations! Published in 2020 at "Brain and Behavior"
DOI: 10.1002/brb3.1614
Abstract: To explore shared brain structural alterations in patients diagnosed with mental disorders who experience own‐thought auditory verbal hallucinations (OTAVHs). read more here.
Keywords: shared brain; structural alterations; brain structural; alterations patients ... See more keywords
Association of disease course and brain structural alterations in major depressive disorder
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DOI: 10.1002/da.23260
Abstract: The investigation of disease course‐associated brain structural alterations in Major Depressive Disorder (MDD) have resulted in heterogeneous findings, possibly due to low reliability of single clinical variables used for defining disease course. The present study… read more here.
Keywords: structural alterations; disease; brain structural; disease course ... See more keywords
Review article: Structural brain alterations in prelingually deaf
Sign Up to like & getrecommendations! Published in 2020 at "NeuroImage"
DOI: 10.1016/j.neuroimage.2020.117042
Abstract: Functional studies show that our brain has a remarkable ability to reorganize itself in the absence of one or more sensory modalities. In this review, we gathered all the available articles investigating structural alterations in… read more here.
Keywords: structural alterations; grey matter; brain alterations; brain ... See more keywords
Chemical and Structural Alterations in the Amorphous Structure of Obsidian due to Nanolites
Sign Up to like & getrecommendations! Published in 2022 at "Microscopy and Microanalysis"
DOI: 10.1017/s1431927621013957
Abstract: Abstract Obsidian is volcanic glass that results from the rapid cooling of silica-rich melt. Nanoscale crystallites precipitate out of the melt prior to solidification and remain embedded in the amorphous matrix. These crystallites provide information… read more here.
Keywords: matrix; amorphous structure; structure; microscopy ... See more keywords
Structural Alterations of Mucins Are Associated with Losses in Functionality.
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DOI: 10.1021/acs.biomac.1c00073
Abstract: Commercial mucin glycoproteins are routinely used as a model to investigate the broad range of important functions mucins fulfill in our bodies, including lubrication, protection against hostile germs, and the accommodation of a healthy microbiome.… read more here.
Keywords: structural alterations; mucin; associated losses; mucins associated ... See more keywords
Mechanism-Based Insights into Removing the Mutagenicity of Aromatic Amines by Small Structural Alterations.
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DOI: 10.1021/acs.jmedchem.1c00514
Abstract: Aromatic and heteroaromatic amines (ArNH2) are activated by cytochrome P450 monooxygenases, primarily CYP1A2, into reactive N-arylhydroxylamines that can lead to covalent adducts with DNA nucleobases. Hereby, we give hands-on mechanism-based guidelines to design mutagenicity-free ArNH2.… read more here.
Keywords: based insights; structural alterations; mechanism; arnh2 ... See more keywords
Individuals at increased risk for development of bipolar disorder display structural alterations similar to people with manifest disease
Sign Up to like & getrecommendations! Published in 2021 at "Translational Psychiatry"
DOI: 10.1038/s41398-021-01598-y
Abstract: In psychiatry, there has been a growing focus on identifying at-risk populations. For schizophrenia, these efforts have led to the development of early recognition and intervention measures. Despite a similar disease burden, the populations at… read more here.
Keywords: risk; structural alterations; individuals increased; increased risk ... See more keywords
Quantitative analysis of nanoscale intranuclear structural alterations in hippocampal cells in chronic alcoholism via transmission electron microscopy imaging.
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DOI: 10.1088/1478-3975/aa5d71
Abstract: Chronic alcoholism is known to alter the morphology of the hippocampus, an important region of cognitive function in the brain. Therefore, to understand the effect of chronic alcoholism on hippocampal neural cells, we employed a… read more here.
Keywords: structural alterations; microscopy; electron microscopy; chronic alcoholism ... See more keywords
Studying nanoscale structural alterations in cancer cells to evaluate ovarian cancer drug treatment, using transmission electron microscopy imaging
Sign Up to like & getrecommendations! Published in 2020 at "Physical Biology"
DOI: 10.1088/1478-3975/ab6abb
Abstract: Understanding nanoscale structural changes can provide information about the physical state of cells/tissues. It has now been shown that increases in nanoscale structural alterations are associated with the progress of carcinogenesis in most cancer cases,… read more here.
Keywords: microscopy; nanoscale structural; treatment; cancer ... See more keywords
Early life stress induces visual dysfunction and retinal structural alterations in adult mice
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DOI: 10.1111/jnc.15752
Abstract: Early life stress (ELS) is defined as a period of severe and/or chronic trauma, as well as environmental/social deprivation or neglect in the prenatal/early postnatal stage. Presently, the impact of ELS on the retina in… read more here.
Keywords: adult; early life; structural alterations; life ... See more keywords
Structural Alterations of MET Trigger Response to MET Kinase Inhibition in Lung Adenocarcinoma Patients
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DOI: 10.1158/1078-0432.ccr-17-3001
Abstract: Purpose: We sought to investigate the clinical response to MET inhibition in patients diagnosed with structural MET alterations and to characterize their functional relevance in cellular models. Experimental Design: Patients were selected for treatment with… read more here.
Keywords: structural alterations; response; response met; inhibition ... See more keywords