Modafinil and its structural analogs as atypical dopamine uptake inhibitors and potential medications for psychostimulant use disorder.
Sign Up to like & getrecommendations! Published in 2020 at "Current opinion in pharmacology"
DOI: 10.1016/j.coph.2020.07.007
Abstract: Pharmacotherapeutics for treatment of psychostimulant use disorder are still an unmet medical goal. Recently, off label use of modafinil (MOD), an approved medication for treatment of sleep disturbances, has been tested as a therapeutic for… read more here.
Keywords: structural analogs; use; psychostimulant use; modafinil structural ... See more keywords
Investigation on the Anticancer Activity of [6]-Gingerol of Zingiber officinale and its Structural Analogs against Skin Cancer.
Sign Up to like & getrecommendations! Published in 2023 at "Current computer-aided drug design"
DOI: 10.2174/1573409919666230418095105
Abstract: AIM Skin cancer is the most common type of cancer caused by the uncontrolled growth of abnormal cells in the epidermis and the outermost skin layer. INTRODUCTION This study aimed to study the anti-skin cancer… read more here.
Keywords: anticancer activity; skin cancer; gingerol; structural analogs ... See more keywords
Recent Advances in Sources, Migration, Public Health, and Surveillance of Bisphenol A and Its Structural Analogs in Canned Foods
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DOI: 10.3390/foods12101989
Abstract: The occurrence of bisphenol A (BPA) and its structural analogs, known as endocrine disruptors is widely reported. Consumers could be exposed to these chemicals through canned foods, leading to health risks. Considerable advances have occurred… read more here.
Keywords: health; canned foods; health surveillance; bisphenol ... See more keywords
Natural Polyphenols Inhibit the Dimerization of the SARS-CoV-2 Main Protease: The Case of Fortunellin and Its Structural Analogs
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26196068
Abstract: 3CL-Pro is the SARS-CoV-2 main protease (MPro). It acts as a homodimer to cleave the large polyprotein 1ab transcript into proteins that are necessary for viral growth and replication. 3CL-Pro has been one of the… read more here.
Keywords: structural analogs; dimerization; cov main; main protease ... See more keywords