Total Syntheses of Basiliolide A1, Basiliolide A2, Basiliolide C, and their Structural Analogues
Sign Up to like & getrecommendations! Published in 2018 at "European Journal of Organic Chemistry"
DOI: 10.1002/ejoc.201701211
Abstract: A small focus library of basiliolides including basiliolide A₁, basiliolide A₂, basiliolide C and their structural analogues have been prepared for the structure-activity relationship study. The synthesis features a cyclopropanation/ring-opening strategy for establishing the C8… read more here.
Keywords: cyclopropanation; total syntheses; structural analogues; basiliolide structural ... See more keywords
PBDEs and their structural analogues in marine environments: Fate and expected formation mechanisms compared with diverse environments.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of hazardous materials"
DOI: 10.1016/j.jhazmat.2017.09.026
Abstract: The concentrations and relative distributions of 27 polybrominated diphenyl ethers (PBDEs) and 17 methoxylated (MeO-) and 8 hydroxylated (OH-) BDEs were determined in marine environments including sediments, bivalves, and seawater along the southern coast of… read more here.
Keywords: structural analogues; marine environments; meo bdes; formation ... See more keywords
Sublimation enthalpy of 1,3-thiazine structural analogues: Experimental determination and estimation based on structural clusterization
Sign Up to like & getrecommendations! Published in 2017 at "Thermochimica Acta"
DOI: 10.1016/j.tca.2017.08.004
Abstract: Abstract The saturated vapor pressures of 4 nonaromatic bicyclic 1,3-thiazine and 1,3-selenazine derivatives have been measured by the method of transpiration by inert gas-carrier in the temperature range of 308–392 K. Based on the experimental data… read more here.
Keywords: sublimation; sublimation enthalpy; structural analogues; thiazine structural ... See more keywords
Hydroxycinnamic acid from Corncob and Its Structural Analogues Inhibit Aβ40 Fibrillation and Attenuate Aβ40-Induced Cytotoxicity.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.0c01841
Abstract: The aggregation of amyloid-β protein (Aβ) is deemed a vital pathological feature of Alzheimer's disease (AD). Hence, inhibiting Aβ aggregation is noticed as a major tactic for the prevention and therapy of AD. Hydroxycinnamic acid,… read more here.
Keywords: structural analogues; small molecules; hydroxycinnamic acid; induced cytotoxicity ... See more keywords
Mimicking Peroxidase Activities with Prussian Blue Nanoparticles and Their Cyanometalate Structural Analogues.
Sign Up to like & getrecommendations! Published in 2017 at "Nano letters"
DOI: 10.1021/acs.nanolett.7b02102
Abstract: Nanoparticles composed of Prussian Blue, PB, and the cyanometalate structural analogues, CuFe, FeCoFe, and FeCo, are examined as inorganic clusters that mimic the functions of peroxidases. PB acts as a superior catalyst for the oxidation… read more here.
Keywords: structural analogues; oxidation; cyanometalate structural; prussian blue ... See more keywords
FRET Studies of Quinolone-Based Bitopic Ligands and Their Structural Analogues at the Muscarinic M1 Receptor.
Sign Up to like & getrecommendations! Published in 2017 at "ACS chemical biology"
DOI: 10.1021/acschembio.6b00828
Abstract: Aiming to design partial agonists as well as allosteric modulators for the M1 muscarinic acetylcholine (M1AChR) receptor, two different series of bipharmacophoric ligands and their structural analogues were designed and synthesized. The hybrids were composed… read more here.
Keywords: structural analogues; bitopic ligands; linker; receptor ... See more keywords
Synthesis of structural analogues of Reversan by ester aminolysis: an access to pyrazolo[1,5-a]pyrimidines from chalcones
Sign Up to like & getrecommendations! Published in 2023 at "RSC Advances"
DOI: 10.1039/d3ra02553e
Abstract: Reversan, a multidrug resistance-associated protein (MRP1) inhibitor described more than a decade ago, is a commercial drug (CAS: 313397-13-6) that has a high price and is six to eight times more potent than known drug… read more here.
Keywords: aminolysis access; analogues reversan; reversan ester; structural analogues ... See more keywords
Crystal violet structural analogues identified by in silico drug repositioning present anti-Trypanosoma cruzi activity through inhibition of proline transporter TcAAAP069
Sign Up to like & getrecommendations! Published in 2020 at "PLoS Neglected Tropical Diseases"
DOI: 10.1371/journal.pntd.0007481
Abstract: Background Crystal violet (CV) was used for several years in blood banks to eliminate the parasite Trypanosoma cruzi in endemic areas in order to prevent transfusion-transmitted Chagas disease. One mechanism of action described for CV… read more here.
Keywords: tcaaap069; proline transporter; structural analogues; proline ... See more keywords
Effect of quinoline based 1,2,3-triazole and its structural analogues on growth and virulence attributes of Candida albicans
Sign Up to like & getrecommendations! Published in 2017 at "PLoS ONE"
DOI: 10.1371/journal.pone.0175710
Abstract: Candida albicans, along with some other non-albicans Candida species, is a group of yeast, which causes serious infections in humans that can be both systemic and superficial. Despite the fact that extensive efforts have been… read more here.
Keywords: structural analogues; quinoline; candida albicans; effect quinoline ... See more keywords