Biointerface Coatings With Structural and Biochemical Properties Modifications of Biomaterials
Sign Up to like & getrecommendations! Published in 2023 at "Advanced Materials Interfaces"
DOI: 10.1002/admi.202202286
Abstract: Designing a successful biological interface for a biomaterial requires the application of concepts from multiple fields, including materials science, surface science, nanoscience, physics, and biochemistry. With current biomaterials, such as polymers, ceramics, and natural materials,… read more here.
Keywords: biointerface coatings; coatings structural; properties modifications; biochemical properties ... See more keywords
Structural and biochemical modifications of model and native membranes of human immune cells in response to the action of zinc oxide nanoparticles
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Applied Toxicology"
DOI: 10.1002/jat.4057
Abstract: The development of nanotechnology has led to the increased production of zinc oxide nanoparticles (ZnO‐NPs) and their application in a wide variety of everyday products. It creates the need for a full assessment of their… read more here.
Keywords: structural biochemical; zno nps; zinc; oxide nanoparticles ... See more keywords
Structural and biochemical insights into FKBP51 as a Hsp90 co-chaperone.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30384
Abstract: The FK506-binding protein 51 (FKBP51) is a high-molecular-weight immunophilin that emerged as an important drug target for stress-related disorders, chronic pain, and obesity. It has been implicated in a plethora of molecular pathways but remains… read more here.
Keywords: fkbp51 hsp90; insights fkbp51; biochemical insights; chaperone ... See more keywords
Disaggregation of Aβ42 for Structural and Biochemical Studies.
Sign Up to like & getrecommendations! Published in 2018 at "Methods in molecular biology"
DOI: 10.1007/978-1-4939-7811-3_20
Abstract: The amyloid-β (Aβ) peptides that form the amyloid fibrils associated with Alzheimer's disease are generated by sequential proteolysis of the amyloid precursor protein by β- and γ-secretase. The two predominant Aβ peptides, Aβ40 and Aβ42,… read more here.
Keywords: disaggregation structural; biochemical studies; biology; structural biochemical ... See more keywords
Structural, Biochemical, and Bioinformatic Basis for Identifying Radical SAM Cyclopropyl Synthases
Sign Up to like & getrecommendations! Published in 2024 at "ACS Chemical Biology"
DOI: 10.1021/acschembio.3c00583
Abstract: The importance of radical S-adenosyl-l-methionine (RS) enzymes in the maturation of ribosomally synthesized and post-translationally modified peptides (RiPPs) continues to expand, specifically for the RS-SPASM subfamily. We recently discovered an RS-SPASM enzyme that installs a… read more here.
Keywords: structural biochemical; cyclopropyl synthases; bioinformatic basis; cyclopropyl ... See more keywords
Structural and biochemical insights into small RNA 3′ end trimming by Arabidopsis SDN1
Sign Up to like & getrecommendations! Published in 2018 at "Nature Communications"
DOI: 10.1038/s41467-018-05942-7
Abstract: A family of DEDDh 3′→5′ exonucleases known as Small RNA Degrading Nucleases (SDNs) initiates the turnover of ARGONAUTE1 (AGO1)-bound microRNAs in Arabidopsis by trimming their 3′ ends. Here, we report the crystal structure of Arabidopsis… read more here.
Keywords: small rna; end trimming; structural biochemical; arabidopsis sdn1 ... See more keywords
Structural and biochemical mechanisms of NLRP1 inhibition by DPP9
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03320-w
Abstract: Nucleotide-binding domain, leucine-rich repeat receptors (NLRs) mediate innate immunity by forming inflammasomes. Activation of the NLR protein NLRP1 requires autocleavage within its function-to-find domain (FIIND)1–7. In resting cells, the dipeptidyl peptidases DPP8 and DPP9 interact… read more here.
Keywords: mechanisms nlrp1; structural biochemical; biochemical mechanisms; dpp9 ... See more keywords
Structural and Biochemical Characterization of Apicomplexan Inorganic Pyrophosphatases
Sign Up to like & getrecommendations! Published in 2017 at "Scientific Reports"
DOI: 10.1038/s41598-017-05234-y
Abstract: Inorganic pyrophosphatases (PPase) participate in energy cycling and they are essential for growth and survival of organisms. Here we report extensive structural and functional characterization of soluble PPases from the human parasites Plasmodium falciparum (PfPPase)… read more here.
Keywords: characterization apicomplexan; structural biochemical; pfppase; biochemical characterization ... See more keywords
The catalytic inactivation of the N-half of human hexokinase 2 and structural and biochemical characterization of its mitochondrial conformation
Sign Up to like & getrecommendations! Published in 2018 at "Bioscience Reports"
DOI: 10.1042/bsr20171666
Abstract: The high proliferation rate of tumor cells demands high energy and metabolites that are sustained by a high glycolytic flux known as the ‘Warburg effect’. The activation and further metabolism of glucose is initiated by… read more here.
Keywords: structural biochemical; human hexokinase; conformation; half ... See more keywords
Fruit micro-structural and biochemical traits diversity analysis of Citrus × sinensis (L.) Osbeck cultivars under Indian sub-tropics
Sign Up to like & getrecommendations! Published in 2025 at "New Zealand Journal of Crop and Horticultural Science"
DOI: 10.1080/01140671.2025.2498444
Abstract: ABSTRACT Structural and biochemical variations in sweet orange cultivars significantly influence their anatomical characteristics, nutritional composition, and potential applications. This study investigates differences in peel, pedicel, and seed anatomy, along with antioxidant activity and nutritional… read more here.
Keywords: structural biochemical; analysis; antioxidant activity; activity ... See more keywords
Structural and biochemical insights into Zn2+-bound EF-hand proteins, EFhd1 and EFhd2
Sign Up to like & getrecommendations! Published in 2023 at "IUCrJ"
DOI: 10.1107/s2052252523001501
Abstract: The EF-hands within the crystal structures of the Zn2+-bound EFhd1 and EFhd2 core domains coordinate Zn2+ ions. EFhd1 and EFhd2 exhibited Ca2+- and Zn2+-independent actin binding and Ca2+- and Zn2+-dependent actin-bundling activity, and these suggest… read more here.
Keywords: ca2 zn2; biochemical insights; zn2 bound; structural biochemical ... See more keywords