Structural and biological characterization of new hybrid drugs joining an HDAC inhibitor to different NO-donors.
Sign Up to like & getrecommendations! Published in 2018 at "European journal of medicinal chemistry"
DOI: 10.1016/j.ejmech.2017.12.047
Abstract: HDAC inhibitors and NO donors have already revealed independently their broad therapeutic potential in pathologic contexts. Here we further investigated the power of their combination in a single hybrid molecule. Nitrooxy groups or substituted furoxan… read more here.
Keywords: structural biological; biological characterization; hdac; new hybrid ... See more keywords
Silk fibroin/sericin 3D sponges: The effect of sericin on structural and biological properties of fibroin.
Sign Up to like & getrecommendations! Published in 2020 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2020.02.316
Abstract: Among naturally occurring polymers, silk fibroin and sericin have attracted much attention in the field of tissue engineering; however, clinical application of silk fibroin/sericin scaffolds in a combined form is mainly questioned due to the… read more here.
Keywords: structural biological; sericin; silk fibroin; fibroin sericin ... See more keywords
Structural and Biological Features of G-Quadruplex Aptamers as Promising Inhibitors of the STAT3 Signaling Pathway
Sign Up to like & getrecommendations! Published in 2023 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms24119524
Abstract: In this paper, we investigate the structural and biological features of G-quadruplex (G4) aptamers as promising antiproliferative compounds affecting the STAT3 signalling pathway. Targeting the STAT3 protein through high-affinity ligands to reduce its levels or… read more here.
Keywords: structural biological; biological features; features quadruplex; quadruplex aptamers ... See more keywords
Textural, Structural and Biological Evaluation of Hydroxyapatite Doped with Zinc at Low Concentrations
Sign Up to like & getrecommendations! Published in 2017 at "Materials"
DOI: 10.3390/ma10030229
Abstract: The present work was focused on the synthesis and characterization of hydroxyapatite doped with low concentrations of zinc (Zn:HAp) (0.01 < xZn < 0.05). The incorporation of low concentrations of Zn2+ ions in the hydroxyapatite… read more here.
Keywords: structural biological; hydroxyapatite doped; spectroscopy; low concentrations ... See more keywords
Structural and Biological Investigations for a Series of N-5 Substituted Pyrrolo[3,2-d]pyrimidines as Potential Anti-Cancer Therapeutics
Sign Up to like & getrecommendations! Published in 2019 at "Molecules"
DOI: 10.3390/molecules24142656
Abstract: Pyrrolo[3,2-d]pyrimidines have been studied for many years as potential lead compounds for the development of antiproliferative agents. Much of the focus has been on modifications to the pyrimidine ring, with enzymatic recognition often modulated by… read more here.
Keywords: substituted pyrrolo; structural biological; investigations series; biological investigations ... See more keywords
Structural and Biological Properties of Water Soluble Polysaccharides from Lotus Leaves: Effects of Drying Techniques
Sign Up to like & getrecommendations! Published in 2021 at "Molecules"
DOI: 10.3390/molecules26154395
Abstract: In the present study, the influence of five drying techniques on the structural and biological properties of polysaccharides from lotus leaves (LLPs) was investigated. Results revealed that the yields, contents of basic chemical components, molecular… read more here.
Keywords: polysaccharides lotus; lotus leaves; structural biological; drying techniques ... See more keywords
The Structural, Biological, and In-Silico Profiling of Novel Capryloyl Tetra-Glucoside and Aliphatic Ester Constituents from the Abutilon indicum Offers New Perspectives on the Treatment of Pain and Inflammation
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11192583
Abstract: Abutilon indicum L. (Malvaceae), more often referred to as Peeli booti, Kanghi, and Kakhi, is a perennial shrub found in many countries of Asia. Traditionally, this plant is used as a diuretic to treat inflammation,… read more here.
Keywords: inflammation; abutilon indicum; structural biological; anti inflammatory ... See more keywords
Mechanical, Structural, and Biological Characteristics of Polylactide/Wollastonite 3D Printed Scaffolds
Sign Up to like & getrecommendations! Published in 2022 at "Polymers"
DOI: 10.3390/polym14193932
Abstract: The present work aimed to study the synergistic response of bioresorbable polylactide/bioactive wollastonite scaffolds towards mechanical stability, mesenchymal stromal cell colonization, and antibacterial activity in the physiological environment. Wollastonite was synthesized at 800 °C within… read more here.
Keywords: polylactide wollastonite; structural biological; microscopy; mechanical structural ... See more keywords