LAUSR

Structural Consequences of N-Methylation of N-Terminus in Oligourea Foldamers.

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1 Published in 2022 at "ChemPlusChem"

DOI: 10.1002/cplu.202200199

Abstract: Oligourea foldamers fold into 2.5-helices. Most of the known modifications of the backbone, such as NH or CO group substitutions or incorporations of non-canonical residues, do not change the conformational properties of the resulting oligourea… read more here.

Keywords: methylation; methylation terminus; oligourea foldamers; terminus oligourea ... See more keywords

Structural consequences of the interaction of puroindolines with gluten proteins.

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0 Published in 2018 at "Food chemistry"

DOI: 10.1016/j.foodchem.2018.01.146

Abstract: The effect of puroindolines (PINs) on structural characteristics of wheat proteins was investigated in Triticum turgidum ssp. durum (cv. Svevo) and Triticum aestivum (cv. Alpowa) and in their respective derivatives in which PIN genes were… read more here.

Keywords: puroindolines gluten; chemistry; structural consequences; interaction puroindolines ... See more keywords

Prediction of structural consequences for disease causing variants in C21orf2 protein using computational approaches

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0 Published in 2019 at "Journal of Biomolecular Structure and Dynamics"

DOI: 10.1080/07391102.2018.1429313

Abstract: Amyotrophic lateral sclerosis (ALS), a progressive motor-neurone disease, affects individuals usually aged between 50 and 70 years. C21orf2, recently identified as the new ALS susceptibility gene, harbours rare missense mutations that cause this fatal disease.… read more here.

Keywords: prediction structural; consequences disease; disease causing; disease ... See more keywords

Evolutionary dynamics and structural consequences of de novo beneficial mutations and mutant lineages arising in a constant environment

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1 Published in 2021 at "BMC Biology"

DOI: 10.1186/s12915-021-00954-0

Abstract: Background Microbial evolution experiments can be used to study the tempo and dynamics of evolutionary change in asexual populations, founded from single clones and growing into large populations with multiple clonal lineages. High-throughput sequencing can… read more here.

Keywords: frequency; beneficial mutations; dynamics structural; structural consequences ... See more keywords

Structural Consequences of Deproteinating the 50S Ribosome

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1 Published in 2022 at "Biomolecules"

DOI: 10.3390/biom12111605

Abstract: Ribosomes are complex ribonucleoprotein particles. Purified 50S ribosomes subjected to high-salt wash, removing a subset of ribosomal proteins (r-proteins), were early shown competent for in vitro assembly into functional 50S subunits. We here used cryo-EM… read more here.

Keywords: rna structure; core; structure; core particles ... See more keywords