Cereblon Modulators Target ZBTB16 and Its Oncogenic Fusion Partners for Degradation via Distinct Structural Degrons.
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DOI: 10.1021/acschembio.0c00674
Abstract: There is a growing interest in using targeted protein degradation as a therapeutic modality in view of its potential to expand the druggable proteome. One avenue to using this modality is via molecular glue based… read more here.
Keywords: degradation; cereblon; cereblon modulators; structural degrons ... See more keywords