Novel structural hybrids of quinoline and thiazole moieties: Synthesis and evaluation of antibacterial and antifungal activities with molecular modeling studies.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.104803
Abstract: One of the best ways to design new biocidal agents is synthesizing hybrid molecules by combining two or more bioactive moieties in a single molecular scaffold. So, new series of quinolines bearing a thiazole moiety… read more here.
Keywords: antibacterial antifungal; structural hybrids; antifungal activities; inhibition growth ... See more keywords
Novel Structural Hybrids on the Base of Benzofuroxans and Furoxans. Mini-Review.
Sign Up to like & getrecommendations! Published in 2017 at "Current topics in medicinal chemistry"
DOI: 10.2174/1568026616666160927145822
Abstract: Hybrid drug strategy is based on the combination of two or more pharmacophores into a new chemical entity to improve the properties of the original compounds or to obtain double action of resulting molecule. Hybrid… read more here.
Keywords: structural hybrids; base benzofuroxans; novel structural; furoxans mini ... See more keywords