Using the Structural Kinome to Systematize Kinase Drug Discovery
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DOI: 10.5772/intechopen.100109
Abstract: Kinase-targeted drug design is challenging. It requires designing inhibitors that can bind to specific kinases, when all kinase catalytic domains share a common folding scaffold that binds ATP. Thus, obtaining the desired selectivity, given the… read more here.
Keywords: using structural; kinome; structural kinome; drug ... See more keywords