Structural modeling of tumor necrosis factor: A protein of immunological importance
Sign Up to like & getrecommendations! Published in 2017 at "Biotechnology and Applied Biochemistry"
DOI: 10.1002/bab.1523
Abstract: Tumor necrosis factor (TNF) is a multifunctional pro‐inflammatory cytokine responsible for various immunoregulatory activities. Upon binding with its receptor, TNF triggers multiple complex signaling pathways such as the activations of nuclear factor kappa B and… read more here.
Keywords: factor; structural modeling; necrosis factor; tumor necrosis ... See more keywords
Structural modeling of a novel SLC38A8 mutation that causes foveal hypoplasia
Sign Up to like & getrecommendations! Published in 2017 at "Molecular Genetics & Genomic Medicine"
DOI: 10.1002/mgg3.266
Abstract: Foveal hypoplasia (FH) in the absence of albinism, aniridia, microphthalmia, or achromatopsia is exceedingly rare, and the molecular basis for the disorder remains unknown. FH is characterized by the absence of both the retinal foveal… read more here.
Keywords: modeling novel; novel slc38a8; structural modeling; foveal hypoplasia ... See more keywords
Structural proteomics, electron cryo-microscopy and structural modeling approaches in bacteria–human protein interactions
Sign Up to like & getrecommendations! Published in 2020 at "Medical Microbiology and Immunology"
DOI: 10.1007/s00430-020-00663-5
Abstract: A central challenge in infection medicine is to determine the structure and function of host–pathogen protein–protein interactions to understand how these interactions facilitate bacterial adhesion, dissemination and survival. In this review, we focus on proteomics,… read more here.
Keywords: protein; microscopy; structural modeling; electron cryo ... See more keywords
Ranking Iranian universities: an interpretative structural modeling approach
Sign Up to like & getrecommendations! Published in 2018 at "Scientometrics"
DOI: 10.1007/s11192-018-2946-9
Abstract: Ranking is widely considered to be an important tool for evaluating the performance, competitiveness, and success of academic institutions. An appropriate ranking system should evaluate the key missions of the higher education system in a… read more here.
Keywords: structural modeling; iranian universities; ranking iranian; interpretative structural ... See more keywords
Integrated structural modeling and super-resolution imaging resolve GPCR oligomers.
Sign Up to like & getrecommendations! Published in 2020 at "Progress in molecular biology and translational science"
DOI: 10.1016/bs.pmbts.2019.11.005
Abstract: Formation of G protein-coupled receptors (GPCRs) dimers and higher order oligomers represents a key mechanism in pleiotropic signaling, yet how individual protomers function within oligomers remains poorly understood. For the Class A/rhodopsin subfamily of glycoprotein… read more here.
Keywords: resolution; resolution imaging; structural modeling; super resolution ... See more keywords
Structural modeling and mechanical characterizing of three-dimensional four-step braided composites: A review
Sign Up to like & getrecommendations! Published in 2019 at "Composite Structures"
DOI: 10.1016/j.compstruct.2018.09.065
Abstract: Abstract The unique structural features of three-dimensional (3D) braided preforms determine an array of excellent mechanical properties of 3D braided composites, such as high strength and low density, great damage tolerance and fatigue performance. In… read more here.
Keywords: unit cell; modeling mechanical; model; braided composites ... See more keywords
Uptake and implementation of Nature-Based Solutions: An analysis of barriers using Interpretive Structural Modeling.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of environmental management"
DOI: 10.1016/j.jenvman.2020.110749
Abstract: Cities increasingly have to find innovative ways to address challenges arising from climate change and urbanization. Nature-based solutions (NBS) have been gaining attention as multifunctional solutions that may help cities to address these challenges. However,… read more here.
Keywords: uptake implementation; implementation; nature based; interpretive structural ... See more keywords
Structural Modeling of the SARS-CoV-2 Spike/Human ACE2 Complex Interface can Identify High-Affinity Variants Associated with Increased Transmissibility
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Biology"
DOI: 10.1016/j.jmb.2021.167051
Abstract: The COVID-19 pandemic has triggered concerns about the emergence of more infectious and pathogenic viral strains. As a public health measure, efficient screening methods are needed to determine the functional effects of new sequence variants.… read more here.
Keywords: human ace2; high affinity; affinity; structural modeling ... See more keywords
Structural modeling and spectroscopic investigation of isolated and hydrochloride tyramine neurotransmitter
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Molecular Structure"
DOI: 10.1016/j.molstruc.2017.06.140
Abstract: Abstract We have reported optimized molecular structure and vibrational spectra of an important biomolecule named tyramine in ten different conformers. The FTIR and FTRaman spectra were recorded in the spectral region 400–4000 cm−1 and 50–4000 cm−1 respectively.… read more here.
Keywords: energy; structural modeling; isolated hydrochloride; spectroscopic investigation ... See more keywords
Dynamic Structural Modeling Revealed That Nilotinib Inhibits Smoothened Signaling
Sign Up to like & getrecommendations! Published in 2019 at "Neurosurgery"
DOI: 10.1093/neuros/nyz310_806
Abstract: Dysregulation of the 7-transmembrane receptors Smoothened (SMO) and other components of the Hedgehog (Hh) signaling pathway causes several cancers, including medulloblastoma (MB) and glioblastoma. However, SMO-specific antagonists produced mixed results in clinical trials, marked by… read more here.
Keywords: dynamic structural; revealed nilotinib; nilotinib inhibits; modeling revealed ... See more keywords
Establishment of Green Supply Chain Management in Steel Industries Using Interpretive Structural Modeling
Sign Up to like & getrecommendations! Published in 2019 at "Perspectives on Global Development and Technology"
DOI: 10.1163/15691497-12341524
Abstract: The state of Chhattisgarh in India has a very large number of steel plants causing pollution in the region. The effect of this pollution exceeds the geographical territory of a unit, and goes much beyond… read more here.
Keywords: interpretive structural; chain management; structural modeling; green supply ... See more keywords