Structural optimizations and bioevaluation of N-substituted acridone derivatives as strong topoisomerase II inhibitors.
Sign Up to like & getrecommendations! Published in 2021 at "Bioorganic chemistry"
DOI: 10.1016/j.bioorg.2021.105543
Abstract: Previously, an array of N-substituted acridone derivatives have been reported as potent topoisomerase II (topo II) inhibitors, and preliminary structure-activity relationship (SAR) outcomes revealed that the linker between 1-NH and N-methyl piperazine motif of the… read more here.
Keywords: structural optimizations; optimizations bioevaluation; acridone derivatives; acridone ... See more keywords